SCHEMBL1811288

SCHEMBL1811288

O=C1c2c(Cl)c(Cl)c(Cl)c(Cl)c2C(=O)N1c1ccc(N2C(=O)c3c(Cl)c(Cl)c(Cl)c(Cl)c3C2=O)cc1

nearest known ligand 0.71

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
CA9 Q16790 3/20 0.71
CA1 P00915 3/20 0.71
CA2 P00918 3/20 0.71
CA7 P43166 3/20 0.71
CA12 O43570 2/20 0.71
NR1H3 Q13133 7/20 0.59
NR1H2 P55055 3/20 0.53
DPP8 Q6V1X1 1/20 0.51
MEN1 O00255 1/20 0.48
KMT2A Q03164 1/20 0.48
GAPDH P04406 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10976600 0.93 CA9 (0.65) CA9CA1CA2CA7CA12
SCHEMBL1816383 0.93 CA9 (0.65) CA9CA1CA2CA7CA12
SCHEMBL16425603 0.89 CA9 (0.61) CA9CA1CA2CA7CA12
SCHEMBL3680527 0.89 DPP8 (0.65) CA9CA1CA2CA7CA12
SCHEMBL9438287 0.88 CA2 (0.74) CA9CA1CA2CA7CA12
SCHEMBL4376929 0.88 NR1H3 (0.62) CA9CA1CA2CA7CA12
SCHEMBL4368968 0.88 NR1H3 (0.62) CA9CA1CA2CA7CA12
SCHEMBL21985847 0.86 CA9 (0.57) CA9CA1CA2CA7CA12
SCHEMBL4380846 0.85 CA9 (0.56) CA9CA1CA2CA7CA12
SCHEMBL20511484 0.84 CA9 (1.00) CA9CA1CA2CA7CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2496636-B1 MORE FLAME-RETARDANT POLYCARBONATE COMPOSITION FOR USE IN EXTRUDED PRODUCTS COVESTRO DEUTSCHLAND AG (DE) 2019-05-15 EP disclosed
US-20120231278-A1 POLYCARBONATE COMPOSITION HAVING IMPROVED FLAME RESISTANCE FOR EXTRUSION APPLICATIONS BAYER INTELLECTUAL PROPERTY GMBH (DE) 2012-09-13 US disclosed
EP-2496636-A2 MORE FLAME-RETARDANT POLYCARBONATE COMPOSITION FOR USE IN EXTRUDED PRODUCTS Bayer MaterialScience AG (DE) 2012-09-12 EP disclosed
US-20110112226-A1 Products with improved flame resistance BAYER MATERIALSCIENCE AG (DE) 2011-05-12 US disclosed
WO-2011054865-A2 MORE FLAME-RETARDANT POLYCARBONATE COMPOSITION FOR USE IN EXTRUDED PRODUCTS BAYER MATERIALSCIENCE AG (DE) 2011-05-12 WO disclosed
EP-2152803-A1 FLAME RETARDANT THERMOPLASTIC RESINOUS COMPOSITION Sabic Innovative Plastics IP B.V. (NL) 2010-02-17 EP disclosed
US-20090137709-A1 POLYOL-CONTAINING, FLAME-RESISTANT POLYCARBONATES, PROCESSES FOR PREPARING THE SAME AND PRODUCTS CONTAINING THE SAME BAYER MATERIALSCIENCE AG (DE) 2009-05-28 US disclosed
US-20080303006-A1 FLAME RETARDANT THERMOPLASTIC RESINOUS COMPOSTION CITIBANK, N.A., AS COLLATERAL AGENT 2008-12-11 US disclosed
WO-2008149260-A1 FLAME RETARDANT THERMOPLASTIC RESINOUS COMPOSITION SABIC INNOVATIVE PLASTICS IP B.V. (US) 2008-12-11 WO disclosed
US-6277905-B1 BLENDING POLYCYCLOHEXYLENEDIMETHYLENE TEREPHTHALATE, RUBBER IMPACT MODIFIER, HALOGENATED ORGANIC COMPOUND CONTAINING AT LEAST ONE IMIDE GROUP AND HAVING SPECIFIED MELTING POINT, REINFORCING FIBER AND SELECTED PHOSPHITE EASTMAN CHEMICAL COMPANY 2001-08-21 US disclosed
US-4399244-A AN IMIDE BAYER AKTIENGESELLSCHAFT (DE) 1983-08-16 US disclosed
EP-0083796-A1 Flame-resistant moulding masses based on polyethylene terephthalate, process for its preparation and its use in the production of articles BAYER AG (DE) 1983-07-20 EP disclosed
US-4374220-A FIREPROOFING; INFLAMMABLE POLYMERIC MACROMOLECULES; HEAT RESISTANCE RAYCHEM CORPORATION (US) 1983-02-15 US disclosed
US-4366276-A Flame-resistant moulding materials based on thermoplastic aromatic polyesters and polyesters carbonates, a process for their production and their use in the production of moulded bodies BAYER AKTIENGESELLSCHAFT (DE) 1982-12-28 US disclosed
US-4313903-A BLENDING WITH AN IMIDE BAYER AKTIENGESELLSCHAFT (DE) 1982-02-02 US disclosed
EP-0042561-A1 Fire-proofed moulding masses based on aromatic thermoplastic polyesters, process for its preparation and use in the production of shaped articles BAYER AG (DE) 1981-12-30 EP disclosed
EP-0030618-A1 Flame-resistant moulding masses based on polyethyleneterephthalate, process for their preparation and their use in producing mouldings BAYER AG (DE) 1981-06-24 EP disclosed
EP-0029930-A1 Use of polyethylene terephthalate moulding masses containing an organic imide in the preparation of crystalline mouldings by injection moulding at low mould temperatures BAYER AG (DE) 1981-06-10 EP disclosed
US-4254011-A CONTAINING A TWO-PHASE CROSSLINKED POLYACRYLATE BAYER AKTIENGESELLSCHAFT (DE) 1981-03-03 US disclosed
US-4208489-A AN ALKALI METAL SALT AND A TETRAHALOGENOPHTHALIMIDE BAYER AKTIENGESELLSCHAFT (DE) 1980-06-17 US disclosed