Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H3 | Q13133 | 9/20 | 0.62 |
| ▸ | CA9 | Q16790 | 3/20 | 0.59 |
| ▸ | CA12 | O43570 | 2/20 | 0.59 |
| ▸ | CA1 | P00915 | 2/20 | 0.59 |
| ▸ | CA2 | P00918 | 1/20 | 0.59 |
| ▸ | CA7 | P43166 | 1/20 | 0.59 |
| ▸ | NR1H2 | P55055 | 4/20 | 0.54 |
| ▸ | FAAH | O00519 | 1/20 | 0.52 |
| ▸ | MGLL | Q99685 | 1/20 | 0.52 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1811288 | 0.88 | CA9 (0.71) | NR1H3CA9CA12CA1CA2 | |
| SCHEMBL4395690 | 0.82 | FAAH (0.57) | NR1H3FAAHMGLL | |
| SCHEMBL1816383 | 0.82 | CA9 (0.65) | NR1H3CA9CA12CA1CA2 | |
| SCHEMBL10976600 | 0.82 | CA9 (0.65) | NR1H3CA9CA12CA1CA2 | |
| SCHEMBL16425603 | 0.78 | CA9 (0.61) | NR1H3CA9CA12CA1CA2 | |
| SCHEMBL3680527 | 0.78 | DPP8 (0.65) | NR1H3CA9CA12CA1CA2 | |
| SCHEMBL4365102 | 0.77 | CA9 (0.57) | NR1H3CA9CA12CA1CA2 | |
| SCHEMBL9438287 | 0.77 | CA2 (0.74) | NR1H3CA9CA12CA1CA2 | |
| SCHEMBL4368968 | 0.77 | NR1H3 (0.62) | NR1H3CA9CA12CA1CA2 | |
| SCHEMBL21985847 | 0.76 | CA9 (0.57) | NR1H3CA9CA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090308001-A1 | Substrate and the application | Wu, Shaobing (US) | 2009-12-17 | — | — | US | disclosed |
| US-20040072929-A1 | Flame retardant compositions | DE SCHRYVER DANIEL A (BE) | 2004-04-15 | — | — | US | disclosed |
| WO-2004003071-A1 | FLAME RETARDANT COMPOSITIONS | ALBEMARLE CORPORATION (US) | 2004-01-08 | — | — | WO | disclosed |
| EP-0604078-B1 | Glass filled flame retardant polyester compositions with improved color | GEN ELECTRIC (US) | 1997-04-23 | — | — | EP | disclosed |
| US-5371123-A | Polyepoxide or polyolefin coating agent | GENERAL ELECTRIC COMPANY (US) | 1994-12-06 | — | — | US | disclosed |
| US-5043371-A | Blend with halogenated bisimide, polytetrafluoroethylene and low molecular weigth polyethylene | POLYPLASTICS CO., LTD. (JP) | 1991-08-27 | — | — | US | disclosed |
| EP-0331456-A2 | Flame-retardant polybutylene terephthalate resin composition and molded article for electrical component | POLYPLASTICS CO. LTD. (JP) | 1989-09-06 | — | — | EP | disclosed |