Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.42 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18113103 | 0.89 | RAB9A (0.45) | NPC1POLBHSP90AA1RAB9ALMNA | |
| SCHEMBL18113123 | 0.87 | EPHX2 (0.40) | NPC1POLBHSP90AA1RAB9ALMNA | |
| SCHEMBL18113317 | 0.87 | MAPT (0.44) | LMNAPKMSMN1; SMN2MEN1KMT2A | |
| SCHEMBL22092402 | 0.86 | PKM (0.43) | NPC1POLBLMNAPKMCYP4F2 | |
| SCHEMBL18113162 | 0.84 | ACHE (0.52) | PKMCYP4F2CYP4A11ALDH1A1SMN1; SMN2 | |
| SCHEMBL18113058 | 0.82 | MAPT (0.42) | NPC1POLBHSP90AA1RAB9ALMNA | |
| SCHEMBL13534776 | 0.81 | RAB9A (0.51) | NPC1POLBHSP90AA1RAB9ALMNA | |
| SCHEMBL18113112 | 0.81 | PKM (0.46) | PKMCYP4F2CYP4A11ALDH1A1SMN1; SMN2 | |
| SCHEMBL19895786 | 0.81 | ACHE (0.47) | LMNAPKMCYP4F2CYP4A11ALDH1A1 | |
| SCHEMBL18113124 | 0.81 | ACHE (0.44) | LMNAPKMCYP4F2CYP4A11SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107428870-B | Catalyst components for the polymerization of olefins | 巴塞尔聚烯烃意大利有限公司 | 2019-06-14 | — | — | CN | disclosed |
| EP-3277736-B1 | CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS | BASELL POLIOLEFINE ITALIA SRL (IT) | 2019-03-27 | — | — | EP | disclosed |
| US-10011668-B2 | Catalyst components for the polymerization of olefins | BASELL POLIOLEFINE ITALIA S.R.L. (IT) | 2018-07-03 | — | — | US | disclosed |
| US-20180057622-A1 | CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS | BASELL POLIOLEFINE ITALIA S.R.L. (IT) | 2018-03-01 | — | — | US | disclosed |
| EP-3277736-A1 | CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS | Basell Poliolefine Italia S.r.l. (IT) | 2018-02-07 | — | — | EP | disclosed |
| CN-107428870-A | Catalyst components for the polymerization of olefins | 巴塞尔聚烯烃意大利有限公司 | 2017-12-01 | — | — | CN | disclosed |
| WO-2016156473-A1 | CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS | BASELL POLIOLEFINE ITALIA S.R.L. (IT) | 2016-10-06 | — | — | WO | disclosed |