Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.79 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | GSK3B | P49841 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dimethenamid SCHEMBL53864 | 0.89 | THRB (1.00) | THRBALDH1A1SMN1; SMN2MEN1KMT2A | |
| Dimethenamid SCHEMBL18223 | 0.89 | THRB (1.00) | THRBALDH1A1SMN1; SMN2MEN1KMT2A | |
| Dimethenamid SCHEMBL5087814 | 0.89 | THRB (1.00) | THRBALDH1A1SMN1; SMN2MEN1KMT2A | |
| Dimethenamid SCHEMBL20723471 | 0.88 | THRB (0.97) | THRBALDH1A1SMN1; SMN2MEN1KMT2A | |
| Dimethenamid SCHEMBL20723446 | 0.88 | THRB (0.97) | THRBALDH1A1SMN1; SMN2MEN1KMT2A | |
| Dimethenamid SCHEMBL28212854 | 0.84 | THRB (0.88) | THRBALDH1A1SMN1; SMN2MEN1KMT2A | |
| Dimethenamid SCHEMBL18115317 | 0.81 | THRB (0.72) | THRBALDH1A1SMN1; SMN2MEN1KMT2A | |
| Metolachor SCHEMBL18115411 | 0.80 | ALDH1A1 (0.52) | THRBALDH1A1SMN1; SMN2MEN1KMT2A | |
| S-Metolachlor SCHEMBL18115404 | 0.80 | ALDH1A1 (0.52) | THRBALDH1A1SMN1; SMN2MEN1KMT2A | |
| Metolachor SCHEMBL17927060 | 0.80 | THRB (0.78) | THRBALDH1A1SMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3280260-A1 | HERBICIDAL MIXTURES | Syngenta Participations AG (CH) | 2018-02-14 | — | — | EP | disclosed |
| EP-3277089-A1 | HERBICIDAL MIXTURES | Syngenta Participations AG (CH) | 2018-02-07 | — | — | EP | disclosed |
| WO-2016162265-A1 | HERBICIDAL MIXTURES | SYNGENTA PARTICIPATIONS AG (CH) | 2016-10-13 | — | — | WO | disclosed |
| WO-2016156241-A1 | HERBICIDAL MIXTURES | SYNGENTA PARTICIPATIONS AG (CH) | 2016-10-06 | — | — | WO | disclosed |