Prosulfocarb

Prosulfocarb

SCHEMBL18115286

CCCN(CCC)C(=O)SCc1ccccc1.C[n+]1ccc(-c2cc[n+](C)cc2)cc1

nearest known ligand 0.41

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.41
MAPK1 P28482 1/20 0.41
SLC22A2 O15244 1/20 0.41
SLC22A1 O15245 1/20 0.41
SLC22A3 O75751 1/20 0.41
SLC6A4 P31645 1/20 0.41
TP53 P04637 1/20 0.39
SMN1; SMN2 Q16637 2/20 0.39
GAA P10253 2/20 0.39
ALDH1A1 P00352 1/20 0.39
LMNA P02545 1/20 0.39
HTT P42858 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
APOBEC3A P31941 1/20 0.38
CTDSP1 Q9GZU7 1/20 0.38
APOBEC3G Q9HC16 1/20 0.38
IDO1 P14902 2/20 0.38
PTPRC P08575 1/20 0.36
GRIN2D O15399 1/20 0.36
GRIN3B O60391 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Prosulfocarb SCHEMBL20845 0.87 TSHR (0.53) TSHRMAPK1TP53SMN1; SMN2ALDH1A1
Prosulfocarb SCHEMBL5799225 0.87 TSHR (0.53) TSHRMAPK1TP53SMN1; SMN2ALDH1A1
Prosulfocarb SCHEMBL9358602 0.86 TSHR (0.52) TSHRMAPK1TP53SMN1; SMN2ALDH1A1
Prosulfocarb SCHEMBL22443002 0.86 TSHR (0.52) TSHRMAPK1TP53SMN1; SMN2ALDH1A1
Prosulfocarb SCHEMBL8981823 0.86 TSHR (0.52) TSHRMAPK1TP53SMN1; SMN2GAA
SCHEMBL27672463 0.82 LMNA (0.47) TSHRMAPK1SLC6A4TP53SMN1; SMN2
Prosulfocarb SCHEMBL15157295 0.81 TSHR (0.46) TSHRMAPK1SLC6A4TP53SMN1; SMN2
Prosulfocarb SCHEMBL8735423 0.81 TSHR (0.46) TSHRMAPK1TP53SMN1; SMN2GAA
Prosulfocarb SCHEMBL18115364 0.80 MEN1 (0.41) TSHRMAPK1TP53SMN1; SMN2ALDH1A1
SCHEMBL987434 0.79 GAA (0.47) TSHRMAPK1SMN1; SMN2GAAALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3280260-A1 HERBICIDAL MIXTURES Syngenta Participations AG (CH) 2018-02-14 EP disclosed
EP-3277089-A1 HERBICIDAL MIXTURES Syngenta Participations AG (CH) 2018-02-07 EP disclosed
WO-2016162265-A1 HERBICIDAL MIXTURES SYNGENTA PARTICIPATIONS AG (CH) 2016-10-13 WO disclosed
WO-2016156241-A1 HERBICIDAL MIXTURES SYNGENTA PARTICIPATIONS AG (CH) 2016-10-06 WO disclosed