SCHEMBL987434

SCHEMBL987434

CCCCN(CCCC)C(=O)SCc1ccccc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 1/20 0.47
HPGD P15428 1/20 0.47
PKM P14618 2/20 0.44
LMNA P02545 2/20 0.44
ALDH1A1 P00352 1/20 0.44
SMN1; SMN2 Q16637 1/20 0.44
HDAC1 Q13547 1/20 0.44
HDAC6 Q9UBN7 1/20 0.44
GRIN2D O15399 1/20 0.43
GRIN3B O60391 1/20 0.43
GRIN1 Q05586 1/20 0.43
GRIN2A Q12879 1/20 0.43
GRIN2B Q13224 1/20 0.43
GRIN2C Q14957 1/20 0.43
GRIN3A Q8TCU5 1/20 0.43
TDP1 Q9NUW8 1/20 0.43
L3MBTL1 Q9Y468 1/20 0.43
MAPT P10636 1/20 0.43
MEN1 O00255 1/20 0.42
KMT2A Q03164 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Prosulfocarb SCHEMBL5799225 0.90 TSHR (0.53) PKMLMNAALDH1A1SMN1; SMN2HDAC1
Prosulfocarb SCHEMBL20845 0.90 TSHR (0.53) PKMLMNAALDH1A1SMN1; SMN2HDAC1
Prosulfocarb SCHEMBL22443002 0.89 TSHR (0.52) PKMLMNAALDH1A1SMN1; SMN2HDAC1
Prosulfocarb SCHEMBL9358602 0.89 TSHR (0.52) PKMLMNAALDH1A1SMN1; SMN2HDAC1
Prosulfocarb SCHEMBL8981823 0.89 TSHR (0.52) GAAPKMLMNAALDH1A1SMN1; SMN2
SCHEMBL11752993 0.86 KDM4E (0.47) HPGDPKMLMNAALDH1A1SMN1; SMN2
SCHEMBL27672463 0.84 LMNA (0.47) GAAHPGDLMNAALDH1A1SMN1; SMN2
Prosulfocarb SCHEMBL8735423 0.83 TSHR (0.46) GAAPKMLMNASMN1; SMN2HDAC1
Prosulfocarb SCHEMBL15157295 0.83 TSHR (0.46) GAAPKMSMN1; SMN2HDAC1HDAC6
SCHEMBL9099861 0.83 LMNA (0.53) HPGDLMNAALDH1A1SMN1; SMN2TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20050090396-A1 Herbicides based on substituted carboxylic acid anilides BAYER CROPSCIENCE AG (DE) 2005-04-28 US claimed
US-20050003963-A1 Herbicides containing substituted thien-3-yl-sulfonylamino(thio)carbonyl-triazolin(thi)one BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2005-01-06 US claimed
EP-1453377-A1 HERBICIDES BASED ON SUBSTITUTED CARBOXYLIC ACID ANILIDES Bayer CropScience AG (DE) 2004-09-08 EP claimed
EP-1429612-A1 HERBICIDES CONTAINING SUBSTITUTED THIEN-3-YL-SULFONYLAMINO(THIO)CARBONYL-TRIAZOLIN(THI)ONE Bayer CropScience AG (DE) 2004-06-23 EP claimed
WO-2003047346-A1 HERBICIDES BASED ON SUBSTITUTED CARBOXYLIC ACID ANILIDES BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2003-06-12 WO claimed
WO-2003026426-A1 HERBICIDES CONTAINING SUBSTITUTED THIEN-3-YL-SULFONYLAMINO(THIO)CARBONYL-TRIAZOLIN(THI)ONE BAYER CROPSCIENCE AG (DE) 2003-04-03 WO claimed
US-9055748-B2 Herbicides containing substituted thien-3-yl-sulfonylamino(thio)carbonyl-triazolin(thi)one BAYER CROPSCIENCE AG (DE) 2015-06-16 US disclosed
US-8648014-B2 Herbicides containing substituted thien-3-yl-sulphonylaminio(thio)carbonyl-triazolin(ethi)ones BAYER CROPSCIENCE AG (DE) 2014-02-11 US disclosed
US-20130178363-A1 HERBICIDES CONTAINING SUBSTITUTED THIEN-3-YL-SULFONYLAMINO(THIO)CARBONYL-TRIAZOLIN(THI)ONE BAYER CROPSCIENCE AG (DE) 2013-07-11 US disclosed
US-8268752-B2 Herbicides containing substituted thien-3-yl-sulphonylamino(thio)carbonyl-triazolin(ethi)ones BAYER CROPSCIENCE AG (DE) 2012-09-18 US disclosed
EP-2301352-A1 Herbicide based on substituted thien-3-yl-sulfonylamino(thio)carbonyl-triazolin(thi)ones and dimethamid Bayer CropScience AG (DE) 2011-03-30 EP disclosed
EP-2279663-A2 Herbicides based on substituted thien-3-yl-sulfonylamino(thio)carbonyl-triazolin(thi)ones and mesotrione Bayer CropScience Aktiengesellschaft (DE) 2011-02-02 EP disclosed
EP-2272365-A2 Herbicides based on substituted thien-3-yl-sulfonylamino(thio)carbonyl-triazolin(thi)ones and sulcotrione Bayer CropScience Aktiengesellschaft (DE) 2011-01-12 EP disclosed
EP-1423005-A1 HERBICIDAL MIXTURES BASED ON SUBSTITUTED ARYL KETONES Bayer CropScience AG (DE) 2004-06-02 EP disclosed
WO-2003026426-A1 HERBICIDES CONTAINING SUBSTITUTED THIEN-3-YL-SULFONYLAMINO(THIO)CARBONYL-TRIAZOLIN(THI)ONE BAYER CROPSCIENCE AG (DE) 2003-04-03 WO disclosed
WO-2003020033-A1 HERBICIDAL MIXTURES BASED ON SUBSTITUTED ARYL KETONES BAYER CROPSCIENCE AG (DE) 2003-03-13 WO disclosed
WO-2003017766-A2 HERBICIDES MADE FROM SUBSTITUTED ARYL KETONES BAYER CROPSCIENCE AG (DE) 2003-03-06 WO disclosed
EP-0135714-B1 SUSTAINED RELEASE COMPOSITIONS FOR BIOLOGICALLY ACTIVE MATERIALS MELAMINE CHEMICALS, INC. (US) 1991-11-06 EP disclosed
US-4029490-A BENZYLTHIOLCARBAMATE ISHIHARA SANGYO KAISHA LTD. (JA) 1977-06-14 US disclosed
US-3930838-A S-BENZYL-N,N-DISEC-BUTYLTHIOCARBAMATE AND ITS USE AS A RICE FIELD HERBICIDE AND A RICE GROWTH STIMULANT MONTECATINI EDISON S.P.A. (IT) 1976-01-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130178363-A1 HERBICIDES CONTAINING SUBSTITUTED THIEN-3-YL-SULFONYLAMINO(THIO)CARBONYL-TRIAZOLIN(THI)ONE TARS2, TST, DDT GAA 1795/4885HPGD 3497/4885PKM 2425/4885
US-20050090396-A1 Herbicides based on substituted carboxylic acid anilides AADAC, NOTUM, NAAA GAA 326/4885HPGD 2310/4885PKM 2451/4885
US-20050003963-A1 Herbicides containing substituted thien-3-yl-sulfonylamino(thio)carbonyl-triazolin(thi)one DDT, TARS2, CBR3 GAA 1644/4885HPGD 3224/4885PKM 2880/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.