Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | IDO1 | P14902 | 5/20 | 0.42 |
| ▸ | NOS3 | P29474 | 1/20 | 0.42 |
| ▸ | NOS1 | P29475 | 1/20 | 0.42 |
| ▸ | NOS2 | P35228 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.41 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Prosulfocarb SCHEMBL5799225 | 0.98 | TSHR (0.53) | TSHRMAPK1TP53MEN1KMT2A | |
| Prosulfocarb SCHEMBL20845 | 0.98 | TSHR (0.53) | TSHRMAPK1TP53MEN1KMT2A | |
| Prosulfocarb SCHEMBL22443002 | 0.97 | TSHR (0.52) | TSHRMAPK1TP53MEN1KMT2A | |
| Prosulfocarb SCHEMBL8981823 | 0.97 | TSHR (0.52) | TSHRMAPK1TP53MEN1KMT2A | |
| SCHEMBL27672463 | 0.92 | LMNA (0.47) | TSHRMAPK1TP53MEN1KMT2A | |
| Prosulfocarb SCHEMBL8735423 | 0.91 | TSHR (0.46) | TSHRMAPK1TP53MEN1KMT2A | |
| Prosulfocarb SCHEMBL15157295 | 0.91 | TSHR (0.46) | TSHRMAPK1TP53MEN1KMT2A | |
| SCHEMBL987434 | 0.89 | GAA (0.47) | TSHRMAPK1MEN1KMT2ASMN1; SMN2 | |
| Prosulfocarb SCHEMBL18115286 | 0.86 | TSHR (0.41) | TSHRMAPK1TP53MEN1KMT2A | |
| SCHEMBL9099861 | 0.84 | LMNA (0.53) | TSHRMAPK1SMN1; SMN2IDO1NOS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0626856-A1 | PHARMACEUTICAL COMPOSITIONS AND THEIR USE FOR TREATING ZINC DEFICIENT DISORDERS | COLBY CORPORATION LIMITED (NZ) | 1994-12-07 | — | — | EP | disclosed |
| WO-1993016708-A1 | PHARMACEUTICAL COMPOSITIONS AND THEIR USE FOR TREATING ZINC DEFICIENT DISORDERS | COLBY CORPORATION LIMITED (NZ) | 1993-09-02 | — | — | WO | disclosed |