Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | PDE4A | P27815 | 5/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 5/20 | 0.35 |
| ▸ | PDE4C | Q08493 | 5/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 5/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 4/20 | 0.33 |
| ▸ | HPGD | P15428 | 3/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | CD274 | Q9NZQ7 | 2/20 | 0.32 |
| ▸ | PDCD1LG2 | Q9BQ51 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18116075 | 0.87 | MAOA (0.35) | MAOAKDM4EGLAPOLBPDE4A | |
| SCHEMBL18116053 | 0.81 | EGFR (0.34) | MAOAKDM4EGLAPOLBPDE4A | |
| SCHEMBL22536840 | 0.77 | NCEH1 (0.32) | KDM4EPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL22536802 | 0.75 | NCEH1 (0.35) | KDM4ELMNARECQLMAPT | |
| SCHEMBL18116050 | 0.74 | LMNA (0.32) | KDM4EPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL29880244 | 0.73 | NCEH1 (0.32) | KDM4EPOLBHSD17B10RECQLALDH1A1 | |
| SCHEMBL22536818 | 0.73 | NCEH1 (0.32) | KDM4EPOLBHSD17B10RECQLALDH1A1 | |
| SCHEMBL18116070 | 0.73 | LMNA (0.33) | KDM4EPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL22536804 | 0.67 | PDE4A (0.33) | KDM4EPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL22536820 | 0.65 | NCEH1 (0.35) | KDM4EPDE4APDE4BPDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3274346-A1 | WATER-SOLUBLE PRODRUGS | Boston Biomedical, Inc. (US) | 2018-01-31 | — | — | EP | disclosed |
| WO-2016157052-A1 | WATER-SOLUBLE PRODRUGS | BOSTON BIOMEDICAL, INC. (US) | 2016-10-06 | — | — | WO | disclosed |