Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | REN | P00797 | 1/20 | 0.32 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.31 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.31 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.31 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.31 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | PDE4A | P27815 | 2/20 | 0.31 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.31 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.31 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | CCR6 | P51684 | 1/20 | 0.30 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.30 |
| ▸ | BACE1 | P56817 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18116050 | 0.94 | LMNA (0.32) | LMNARENL3MBTL1PDE4APDE4B | |
| SCHEMBL18116057 | 0.91 | PDE4A (0.33) | LMNARENL3MBTL1PDE4APDE4B | |
| SCHEMBL22772346 | 0.79 | ALDH1A1 (0.35) | LMNAL3MBTL1PDE4APDE4BPDE4C | |
| SCHEMBL18116077 | 0.78 | KDM4E (0.33) | LMNARENL3MBTL1PDE4APDE4B | |
| SCHEMBL22536802 | 0.73 | NCEH1 (0.35) | LMNAKDM4E | |
| SCHEMBL18116047 | 0.73 | MAOA (0.36) | LMNAPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL22536818 | 0.71 | NCEH1 (0.32) | L3MBTL1KDM4E | |
| SCHEMBL29880244 | 0.71 | NCEH1 (0.32) | L3MBTL1KDM4E | |
| SCHEMBL22536840 | 0.70 | NCEH1 (0.32) | LMNAPDE4APDE4BPDE4CPDE4D | |
| Hydrochloric Acid SCHEMBL22157868 | 0.67 | GAA (0.37) | LMNAL3MBTL1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3274346-A1 | WATER-SOLUBLE PRODRUGS | Boston Biomedical, Inc. (US) | 2018-01-31 | — | — | EP | disclosed |
| WO-2016157052-A1 | WATER-SOLUBLE PRODRUGS | BOSTON BIOMEDICAL, INC. (US) | 2016-10-06 | — | — | WO | disclosed |