Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | FNTA | P49354 | 1/20 | 0.34 |
| ▸ | FNTB | P49356 | 1/20 | 0.34 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.34 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.34 |
| ▸ | CASP3 | P42574 | 1/20 | 0.34 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.34 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.34 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.33 |
| ▸ | LDHA | P00338 | 1/20 | 0.33 |
| ▸ | LDHB | P07195 | 1/20 | 0.33 |
| ▸ | CBLB | Q13191 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14853086 | 1.00 | FDPS (0.38) | FDPSSMN1; SMN2LMNAMEN1KMT2A | |
| SCHEMBL690630 | 0.89 | ITGA4 (0.43) | FDPSSMN1; SMN2LMNAMEN1KMT2A | |
| SCHEMBL690631 | 0.89 | ITGA4 (0.43) | FDPSSMN1; SMN2LMNAMEN1KMT2A | |
| SCHEMBL18994931 | 0.87 | FDPS (0.41) | FDPSSMN1; SMN2LMNAMEN1KMT2A | |
| SCHEMBL888737 | 0.86 | LMNA (0.41) | FDPSSMN1; SMN2LMNAMEN1KMT2A | |
| SCHEMBL10122823 | 0.86 | LMNA (0.41) | FDPSSMN1; SMN2LMNAMEN1KMT2A | |
| SCHEMBL12841633 | 0.86 | FDPS (0.37) | FDPSSMN1; SMN2LMNAMEN1KMT2A | |
| SCHEMBL8907899 | 0.85 | FDPS (0.39) | FDPSSMN1; SMN2LMNAMEN1KMT2A | |
| SCHEMBL19364781 | 0.83 | LMNA (0.35) | FDPSSMN1; SMN2LMNAMEN1KMT2A | |
| SCHEMBL25227617 | 0.78 | KLK5 (0.43) | FDPSITGA4ITGB7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2400846-B1 | HEPATITIS C VIRUS INHIBITORS | ENANTA PHARM INC (US) | 2016-10-05 | — | — | EP | disclosed |