Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSB | P07858 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 7/20 | 0.50 |
| ▸ | LMNA | P02545 | 4/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | HTT | P42858 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | IDO1 | P14902 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18347734 | 0.85 | LMNA (0.48) | CTSBMAPTLMNAGAAMEN1 | |
| SCHEMBL30064935 | 0.84 | KCNJ11 (0.53) | CTSBMAPTLMNAGAAMEN1 | |
| SCHEMBL6839572 | 0.84 | KCNJ11 (0.53) | CTSBMAPTLMNAGAAMEN1 | |
| SCHEMBL28620655 | 0.81 | MAPT (0.45) | MAPTLMNAGAAMEN1KMT2A | |
| SCHEMBL18122171 | 0.81 | HTT (0.46) | MAPTLMNAGAAMEN1KMT2A | |
| SCHEMBL31490630 | 0.79 | MAPT (0.51) | CTSBMAPTLMNAGAAMEN1 | |
| SCHEMBL5565461 | 0.78 | MAPT (0.48) | CTSBMAPTLMNAGAAMEN1 | |
| SCHEMBL11619937 | 0.78 | ALDH1A1 (0.53) | CTSBMAPTLMNAGAAMEN1 | |
| SCHEMBL18122170 | 0.76 | AKR1C3 (0.48) | MAPTLMNAMEN1KMT2AALDH1A1 | |
| SCHEMBL249599 | 0.75 | KCNMA1 (0.56) | MAPTMEN1KMT2ASMN1; SMN2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016159576-A2 | 1,2-NAPHTHOQUINONE DERIVATIVE AND METHOD FOR PREPARING SAME | 주식회사 케이티앤지생명과학 | 2016-10-06 | — | — | WO | disclosed |