Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 3/20 | 0.39 |
| ▸ | HRH4 | Q9H3N8 | 3/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.39 |
| ▸ | NOS3 | P29474 | 1/20 | 0.38 |
| ▸ | NOS1 | P29475 | 1/20 | 0.38 |
| ▸ | NOS2 | P35228 | 1/20 | 0.38 |
| ▸ | PARP1 | P09874 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | HRH2 | P25021 | 2/20 | 0.36 |
| ▸ | HRH1 | P35367 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 3/20 | 0.35 |
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | OGA | O60502 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31347405 | 0.91 | ALDH1A1 (0.38) | KCNH2HRH4HRH3NOS3NOS1 | |
| SCHEMBL31347400 | 0.91 | ALDH1A1 (0.38) | KCNH2HRH4HRH3NOS3NOS1 | |
| SCHEMBL29967583 | 0.89 | HSD17B10 (0.38) | KCNH2HRH4HRH3NOS3NOS1 | |
| SCHEMBL18123538 | 0.89 | CYP1A2 (0.41) | KCNH2HRH4HRH3NOS3NOS1 | |
| SCHEMBL29967332 | 0.87 | DYRK1A (0.38) | KCNH2HRH4HRH3NOS3NOS1 | |
| SCHEMBL10077307 | 0.85 | EGFR (0.33) | KCNH2HRH4HRH3PARP1HRH2 | |
| SCHEMBL10282500 | 0.83 | NOS3 (0.41) | NOS3NOS1NOS2PARP1KDM4E | |
| SCHEMBL30893589 | 0.83 | NOS3 (0.41) | NOS3NOS1NOS2PARP1KDM4E | |
| SCHEMBL14184289 | 0.82 | TP53 (0.46) | KCNH2TP53 | |
| SCHEMBL803417 | 0.80 | CYP1A2 (0.50) | NOS3NOS1NOS2PARP1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016156076-A1 | PESTICIDALLY ACTIVE CARBAMOYLATED AND THIOCARBAMOYLATED OXIME DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2016-10-06 | — | — | WO | disclosed |