Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | STAT3 | P40763 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | PDE4A | P27815 | 1/20 | 0.32 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.32 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.32 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.32 |
| ▸ | ELANE | P08246 | 1/20 | 0.32 |
| ▸ | F2 | P00734 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18123781 | 0.88 | LMNA (0.37) | LMNARECQLALDH1A1MAPTSTAT3 | |
| SCHEMBL18123699 | 0.85 | MAPT (0.37) | LMNARECQLALDH1A1MAPTSTAT3 | |
| SCHEMBL18123783 | 0.81 | MAPT (0.37) | LMNARECQLALDH1A1MAPTSTAT3 | |
| SCHEMBL18123775 | 0.79 | ALDH1A1 (0.43) | LMNARECQLALDH1A1MAPTSTAT3 | |
| SCHEMBL18123782 | 0.77 | CYP3A4 (0.39) | ALDH1A1MAPTKDM4EGAAHPGD | |
| SCHEMBL18123704 | 0.77 | CYP3A4 (0.39) | ALDH1A1MAPTKDM4EGAAHPGD | |
| SCHEMBL18123828 | 0.76 | LMNA (0.39) | LMNARECQLALDH1A1MAPTSTAT3 | |
| SCHEMBL12494851 | 0.73 | LMNA (0.39) | LMNARECQLALDH1A1MAPTSTAT3 | |
| SCHEMBL12493926 | 0.73 | MAPT (0.48) | LMNARECQLALDH1A1MAPTSTAT3 | |
| SCHEMBL18867274 | 0.72 | HPGD (0.43) | LMNAALDH1A1MAPTKMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016157052-A1 | WATER-SOLUBLE PRODRUGS | BOSTON BIOMEDICAL, INC. (US) | 2016-10-06 | — | — | WO | disclosed |