Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | GAA | P10253 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | STAT3 | P40763 | 3/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | PDE4A | P27815 | 4/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 4/20 | 0.38 |
| ▸ | PDE4C | Q08493 | 4/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 4/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18123776 | 0.79 | LMNA (0.33) | ALDH1A1GAAMAPTKDM4EHSD17B10 | |
| SCHEMBL20851793 | 0.72 | LMNA (0.43) | ALDH1A1GAAMAPTKDM4EHSD17B10 | |
| SCHEMBL14656256 | 0.72 | KDM4E (0.50) | ALDH1A1GAAMAPTKDM4EHSD17B10 | |
| SCHEMBL29488 | 0.69 | LMNA (0.50) | ALDH1A1GAAMAPTKDM4EHSD17B10 | |
| SCHEMBL10025575 | 0.69 | HSP90AA1 (0.64) | ALDH1A1MAPTKDM4EMEN1POLB | |
| SCHEMBL12493926 | 0.68 | MAPT (0.48) | ALDH1A1GAAMAPTKDM4EHSD17B10 | |
| SCHEMBL18123828 | 0.67 | LMNA (0.39) | ALDH1A1GAAMAPTKDM4EHSD17B10 | |
| SCHEMBL8342247 | 0.67 | LMNA (0.55) | ALDH1A1GAAMAPTKDM4EHSD17B10 | |
| SCHEMBL17145859 | 0.65 | PDE4A (0.40) | ALDH1A1GAAMAPTKDM4EHSD17B10 | |
| SCHEMBL16795594 | 0.65 | KDM4E (0.73) | ALDH1A1GAAMAPTKDM4EHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016157052-A1 | WATER-SOLUBLE PRODRUGS | BOSTON BIOMEDICAL, INC. (US) | 2016-10-06 | — | — | WO | disclosed |