Ammonia Solution, Strong

Ammonia Solution, Strong

SCHEMBL1812467

N.O=C(O)c1cccc(Cl)c1

nearest known ligand 0.63

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PARP1 P09874 1/20 0.63
NPC1 O15118 3/20 0.62
RAB9A P51151 3/20 0.62
RXRA P19793 1/20 0.60
RXRB P28702 1/20 0.60
ERCC5 P28715 1/20 0.56
FEN1 P39748 1/20 0.56
TPMT P51580 1/20 0.56
CA12 O43570 1/20 0.56
CA1 P00915 1/20 0.56
CA2 P00918 1/20 0.56
CA6 P23280 1/20 0.56
CA9 Q16790 1/20 0.56
NR4A2 P43354 1/20 0.56
KCNK3 O14649 1/20 0.53
KCNK9 Q9NPC2 1/20 0.53
MRGPRX4 Q96LA9 1/20 0.53
L3MBTL1 Q9Y468 2/20 0.53
KMO O15229 1/20 0.52
CYP1A2 P05177 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ammonia Solution, Strong SCHEMBL30477652 1.00 PARP1 (0.63) PARP1NPC1RAB9ARXRARXRB
Benzene SCHEMBL28107074 0.98 PARP1 (0.65) PARP1NPC1RAB9ARXRARXRB
SCHEMBL16865710 0.98 PARP1 (0.65) PARP1NPC1RAB9ARXRARXRB
SCHEMBL38766 0.98 PARP1 (0.65) PARP1NPC1RAB9ARXRARXRB
SCHEMBL29360692 0.98 PARP1 (0.65) PARP1NPC1RAB9ARXRARXRB
SCHEMBL28134936 0.98 PARP1 (0.65) PARP1NPC1RAB9ARXRARXRB
SCHEMBL10602066 0.95 PARP1 (0.63) PARP1NPC1RAB9ARXRARXRB
Hydrochloric Acid SCHEMBL3535766 0.95 PARP1 (0.63) PARP1NPC1RAB9ARXRARXRB
SCHEMBL9317541 0.95 PARP1 (0.63) PARP1NPC1RAB9ARXRARXRB
Water SCHEMBL1456948 0.95 PARP1 (0.63) PARP1NPC1RAB9ARXRARXRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110396056-A A method of preparing m-chlorobenzene nitrile SANMENXIA HUANYU BIOCHEMICAL TECH CO LTD 2019-11-01 CN claimed
EP-3710422-B1 PROCESS FOR THE PREPARATION OF ENANTIOMERICALLY AND DIASTEREOMERICALLY ENRICHED CYCLOBUTANE AMINES AND AMIDES SYNGENTA CROP PROTECTION AG (CH) 2026-01-07 EP disclosed
CN-111417618-B Process for preparing enantiomerically and diastereomerically enriched cyclobutane amines and amides 先正达参股股份有限公司 2023-06-30 CN disclosed
US-11053188-B2 Process for the preparation of enantiomerically and diastereomerically enriched cyclobutane amines and amides SYNGENTA PARTICIPATIONS AG (CH) 2021-07-06 US disclosed
US-20200407311-A1 PROCESS FOR THE PREPARATION OF ENANTIOMERICALLY AND DIASTEREOMERICALLY ENRICHED CYCLOBUTANE AMINES AND AMIDES SYNGENTA PARTICIPATIONS AG (CH) 2020-12-31 US disclosed
CN-111417618-A Process for preparing enantiomerically and diastereomerically enriched cyclobutaneamines and cyclobutaneamides 先正达参股股份有限公司 2020-07-14 CN disclosed
CN-110467541-A A method of m-chlorobenzene nitrile is directly synthesized by m-chlorobenzoic acid and urea SANMENXIA HUANYU BIOCHEMISTRY TECH CO LTD 2019-11-19 CN disclosed
CN-110396056-A A method of preparing m-chlorobenzene nitrile SANMENXIA HUANYU BIOCHEMICAL TECH CO LTD 2019-11-01 CN disclosed
CN-110396056-A A method of preparing m-chlorobenzene nitrile SANMENXIA HUANYU BIOCHEMICAL TECH CO LTD 2019-11-01 CN disclosed
CN-110062900-A Colorant dispersion liquid for color filter, colored resin composition for color filter, and display device DNP精细化工股份有限公司 2019-07-26 CN disclosed
EP-0927751-B1 Smear resistant pigmented ink jet inks containing Beta-diketone or ureido dispersants DU PONT (US) 2002-09-11 EP disclosed
US-6037390-A WATERPROOFING, STORAGE STABILITY E. I. DU PONT DE NEMOURS AND COMPANY (US) 2000-03-14 US disclosed
EP-0927751-A1 Smear resistant pigmented ink jet inks containing Beta-diketone or ureido dispersants E.I. DU PONT DE NEMOURS AND COMPANY (US) 1999-07-07 EP disclosed
WO-1998044058-A1 HIGH INTENSITY ULTRASONIC MILLING IN THE PREPARATION OF INK JET INKS E.I. DU PONT DE NEMOURS AND COMPANY (US) 1998-10-08 WO disclosed
US-5512418-A WITH ACTIVE LAYER CONTAINING CATIONIC POLYMER E. I. DU PONT DE NEMOURS AND COMPANY (US) 1996-04-30 US disclosed
US-5019634-A Group transfer living polymer grafted to an initiator support E. I. DU PONT DE NEMOURS AND COMPANY (US) 1991-05-28 US disclosed
US-5003004-A Star Polymers E. I. DU PONT DE NEMOURS AND COMPANY (US) 1991-03-26 US disclosed
US-4940760-A ATTACHED TO SOLID SUPPORT THAT IS INSOLUBLE IN REACTION MEDIUM; ORGANO-SILICON,-GERMANIUM OR-TIN COMPOUND E. I. DU PONT DE NEMOURS AND COMPANY (US) 1990-07-10 US disclosed
US-4094886-A Process for producing allyl alcohol derivatives useful in prostaglandin synthesis (ZAIDANHOJIN) SAGAMI CHEMICAL RESEARCH CENTER (JA) 1978-06-13 US disclosed
US-4073799-A Process for producing 3-formylcyclopentanone derivatives (ZAIDANHOJIN) SAGAMI CHEMICAL RESEARCH CENTER (JA) 1978-02-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200407311-A1 PROCESS FOR THE PREPARATION OF ENANTIOMERICALLY AND DIASTEREOMERICALLY ENRICHED CYCLOBUTANE AMINES AND AMIDES TBCB, ADORA2B, ADRA2B PARP1 1044/4885NPC1 4771/4885RAB9A 4543/4885
US-11053188-B2 Process for the preparation of enantiomerically and diastereomerically enriched cyclobutane amines and amides TBCB, ADORA2B, CCNB3 PARP1 1014/4885NPC1 4752/4885RAB9A 4570/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.