SCHEMBL18125342

SCHEMBL18125342

c1ccc(-c2ccc(N(c3ccc(-c4ccccc4)cc3)c3ccc4c(c3)oc3cc(-c5cc6ccc7cccc8oc(c5)c6c78)ccc34)cc2)cc1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PGR P06401 2/20 0.36
HCRTR1 O43613 2/20 0.34
CYP19A1 P11511 1/20 0.34
CCNC P24863 1/20 0.34
CDK8 P49336 1/20 0.34
HSD17B1 P14061 3/20 0.34
HSD17B2 P37059 3/20 0.34
MMP12 P39900 1/20 0.34
MMP13 P45452 1/20 0.34
MEN1 O00255 1/20 0.32
NPC1 O15118 1/20 0.32
CASP3 P42574 1/20 0.32
RAB9A P51151 1/20 0.32
KMT2A Q03164 1/20 0.32
SENP8 Q96LD8 1/20 0.32
SENP7 Q9BQF6 1/20 0.32
SENP6 Q9GZR1 1/20 0.32
ESR1 P03372 4/20 0.32
ESR2 Q92731 4/20 0.32
PRKDC P78527 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18125344 0.96 HCRTR1 (0.36) PGRHCRTR1CYP19A1CCNCCDK8
SCHEMBL18125356 0.91 PGR (0.38) PGRCYP19A1CCNCCDK8HSD17B1
SCHEMBL18125336 0.91 PGR (0.40) PGRCYP19A1CCNCCDK8HSD17B1
SCHEMBL18125348 0.91 CCNC (0.39) PGRCYP19A1CCNCCDK8HSD17B1
SCHEMBL18125337 0.91 CCNC (0.39) PGRCYP19A1CCNCCDK8HSD17B1
SCHEMBL18125322 0.91 CCNC (0.39) PGRCYP19A1CCNCCDK8HSD17B1
SCHEMBL18125329 0.91 CCNC (0.39) PGRCYP19A1CCNCCDK8HSD17B1
SCHEMBL18125334 0.90 CCNC (0.38) PGRCYP19A1CCNCCDK8HSD17B1
SCHEMBL18125335 0.90 CCNC (0.38) PGRCYP19A1CCNCCDK8HSD17B1
SCHEMBL18125331 0.88 CCNC (0.36) PGRCYP19A1CCNCCDK8NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10043980-B2 Compound and organic light-emitting device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2018-08-07 US disclosed
US-10043980-B2 Compound and organic light-emitting device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2018-08-07 US disclosed
US-20160293847-A1 COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2016-10-06 US disclosed
US-20160293847-A1 COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2016-10-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10043980-B2 Compound and organic light-emitting device including the same OCIAD1, AOX1, CRY1 PGR 2778/4885HCRTR1 651/4885CYP19A1 100/4885
US-20160293847-A1 COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME OCIAD1, AOX1, CRY1 PGR 2778/4885HCRTR1 651/4885CYP19A1 100/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.