Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 1/20 | 0.57 |
| ▸ | CACNA1C | Q13936 | 3/20 | 0.50 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.50 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.50 |
| ▸ | CACNB1 | Q02641 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | GRM5 | P41594 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | DPP8 | Q6V1X1 | 3/20 | 0.46 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.46 |
| ▸ | FAP | Q12884 | 1/20 | 0.46 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.46 |
| ▸ | KDM1A | O60341 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | CACNA1F | O60840 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL16826402 | 0.99 | DPP4 (0.59) | DPP4CACNA1CCACNA2D1CACNA1BCACNB1 | |
| SCHEMBL16826431 | 0.82 | DPP4 (0.48) | DPP4CACNA1CCACNA2D1CACNA1BCACNB1 | |
| SCHEMBL26331270 | 0.81 | CACNA2D1 (0.60) | CACNA1CCACNA2D1CACNA1BCACNB1SMN1; SMN2 | |
| SCHEMBL20353635 | 0.78 | FAAH (0.60) | MEN1KMT2ANPSR1KDM1ACHRM4 | |
| SCHEMBL3970912 | 0.77 | MEN1 (0.76) | SMN1; SMN2CYP2C19MEN1KMT2ANPSR1 | |
| SCHEMBL379160 | 0.77 | MEN1 (0.76) | SMN1; SMN2CYP2C19MEN1KMT2ANPSR1 | |
| SCHEMBL7393652 | 0.77 | MEN1 (0.76) | SMN1; SMN2CYP2C19MEN1KMT2ANPSR1 | |
| SCHEMBL4814264 | 0.77 | MEN1 (0.76) | SMN1; SMN2CYP2C19MEN1KMT2ANPSR1 | |
| SCHEMBL6632417 | 0.76 | MEN1 (0.62) | DPP4SMN1; SMN2CYP2C19MEN1KMT2A | |
| SCHEMBL2770527 | 0.76 | RORC (0.48) | DPP4SMN1; SMN2CYP2C19MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160297823-A1 | SUBSTITUTED AMINO TRIAZOLES, AND METHODS USING SAME | INSTITUTE FOR DRUG DISCOVERY, LLC | 2016-10-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160297823-A1 | SUBSTITUTED AMINO TRIAZOLES, AND METHODS USING SAME | CMA1, CHIA, AADAC | DPP4 274/4885CACNA1C 4128/4885CACNA2D1 2023/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.