Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 1/20 | 0.44 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.38 |
| ▸ | CACNG8 | Q8WXS5 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | AR | P10275 | 2/20 | 0.38 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.37 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.35 |
| ▸ | PSMB8 | P28062 | 4/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29741728 | 1.00 | DYRK1A (0.44) | DYRK1AGRIA1CACNG8TSHRAR | |
| SCHEMBL24084247 | 0.88 | ADORA2A (0.43) | DYRK1AARCYP11B2CA1CA2 | |
| SCHEMBL1533157 | 0.83 | TSHR (0.46) | TSHRTRPV4NOTUMCA1CA2 | |
| SCHEMBL16958919 | 0.79 | CYP1A2 (0.36) | TSHRNOTUMALDH1A1MEN1GAA | |
| SCHEMBL9845641 | 0.79 | TRPV4 (0.43) | DYRK1AARTRPV4CYP11B2KDM4E | |
| SCHEMBL15540429 | 0.79 | CYP1A2 (0.36) | TSHRALDH1A1MEN1GAAKMT2A | |
| SCHEMBL22316495 | 0.78 | ADORA2A (0.40) | DYRK1ATSHRARCYP11B2ADORA2A | |
| SCHEMBL24084232 | 0.78 | BCAT1 (0.41) | DYRK1AGRIA1CACNG8ARCYP11B2 | |
| SCHEMBL16954084 | 0.77 | TSHR (0.38) | DYRK1AGRIA1CACNG8TSHRTRPV4 | |
| SCHEMBL15541355 | 0.77 | CYP1A2 (0.35) | TSHRNOTUMALDH1A1MEN1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 173 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3997096-B1 | NEW HETEROCYCLIC COMPOUNDS | HOFFMANN LA ROCHE (CH) | 2024-08-28 | — | — | EP | claimed |
| CN-110302733-A | Preparation method of double-halogen nitrogen-containing heterocyclic compound | 北京六合宁远科技有限公司 | 2019-10-08 | — | — | CN | claimed |
| CN-109293503-A | A kind of preparation method of the fluoro- 3- chlorobenzoic acid of 2,4,5- tri- | 浙江工业大学上虞研究院有限公司 | 2019-02-01 | — | — | CN | claimed |
| CN-106279086-B | Ganoderma lucidum furans A and its pharmaceutical composition and its application in pharmacy and food | 中国科学院昆明植物研究所 | 2018-03-06 | — | — | CN | claimed |
| CN-106279086-A | Ganoderma furan A and pharmaceutical composition thereof and its application in pharmacy and food | 中国科学院昆明植物研究所 | 2017-01-04 | — | — | CN | claimed |
| EP-0073372-B1 | PROCESS FOR PRODUCING 2,6-DIFLUOROBENZONITRILE | ISHIHARA SANGYO KAISHA, LTD. (JP) | 1984-08-01 | — | — | EP | claimed |
| US-4406841-A | HYDROGENATION OF 3-CHLORO- (OR 3,5-DICHLORO-2,6-DIFLUOROBENZONITRILE, PALLADIUM OR PLATINUM CATALYST | ISHIHARA SANGYO KAISHA LTD. (JP) | 1983-09-27 | — | — | US | claimed |
| EP-0073372-A1 | Process for producing 2,6-difluorobenzonitrile | ISHIHARA SANGYO KAISHA, LTD. (JP) | 1983-03-09 | — | — | EP | claimed |
| JP-1294653-A | — | — | None | — | — | JP | disclosed |
| JP-1311052-A | — | — | None | — | — | JP | disclosed |
| US-12570799-B2 | Crystalline polyethernitrile | TORAY INDUSTRIES, INC. (JP) | 2026-03-10 | — | — | US | disclosed |
| EP-4680333-A1 | PHENYLPIPERIDINE DERIVATIVES AS INHIBITORS OF GLUTAMINYL-PEPTIDE CYCLOTRANSFERASE AND GLUTAMINYL-PEPTIDE CYCLOTRANSFERASE LIKE PROTEIN | Boehringer Ingelheim International GmbH (DE) | 2026-01-21 | — | — | EP | disclosed |
| US-20250304576-A1 | IKK INHIBITORS | CANCER RESEARCH TECH LTD (GB) | 2025-10-02 | — | — | US | disclosed |
| US-20250243183-A1 | IMIDAZOLYL PYRIMIDINYLAMINE COMPOUNDS AS CDK2 INHIBITORS | INCYTE CORPORATION | 2025-07-31 | — | — | US | disclosed |
| US-4406841-A | HYDROGENATION OF 3-CHLORO- (OR 3,5-DICHLORO-2,6-DIFLUOROBENZONITRILE, PALLADIUM OR PLATINUM CATALYST | ISHIHARA SANGYO KAISHA LTD. (JP) | 1983-09-27 | — | — | US | disclosed |
| US-4406841-A | HYDROGENATION OF 3-CHLORO- (OR 3,5-DICHLORO-2,6-DIFLUOROBENZONITRILE, PALLADIUM OR PLATINUM CATALYST | ISHIHARA SANGYO KAISHA LTD. (JP) | 1983-09-27 | — | — | US | disclosed |
| EP-0073372-A1 | Process for producing 2,6-difluorobenzonitrile | ISHIHARA SANGYO KAISHA, LTD. (JP) | 1983-03-09 | — | — | EP | disclosed |
| EP-0073372-A1 | Process for producing 2,6-difluorobenzonitrile | ISHIHARA SANGYO KAISHA, LTD. (JP) | 1983-03-09 | — | — | EP | disclosed |
| US-4351777-A | Preparation of fluorobenzonitriles | RHONE-POULENC INDUSTRIES (FR) | 1982-09-28 | — | — | US | disclosed |
| US-4209457-A | Production of halogenated benzonitriles | I.S. C. Chemicals Limited (GB) | 1980-06-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250304576-A1 | IKK INHIBITORS | NFKBIA, IKBKE, IKBKB | DYRK1A 707/4885GRIA1 2707/4885CACNG8 4046/4885 |
| US-12570799-B2 | Crystalline polyethernitrile | AR, NR5A1, ESRRA | DYRK1A 4824/4885GRIA1 884/4885CACNG8 2700/4885 |
| US-20250243183-A1 | IMIDAZOLYL PYRIMIDINYLAMINE COMPOUNDS AS CDK2 INHIBITORS | CDK2, CDK4, CDK2AP2 | DYRK1A 1027/4885GRIA1 3172/4885CACNG8 4461/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.