SCHEMBL181330

SCHEMBL181330

CCCCCCCCc1ccc2c(OC(C)=O)cccc2c1

nearest known ligand 0.53

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
PPARG P37231 4/20 0.53
PPARA Q07869 4/20 0.53
PTGS2 P35354 5/20 0.49
TRPV1 Q8NER1 1/20 0.48
S1PR1 P21453 1/20 0.46
S1PR3 Q99500 1/20 0.46
LPL P06858 1/20 0.45
LIPG Q9Y5X9 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27342003 0.90 PPARG (0.53) PPARGPPARAPTGS2TRPV1LPL
SCHEMBL27524531 0.84 PPARG (0.46) PPARGPPARAPTGS2TRPV1
SCHEMBL27771807 0.83 PTGS2 (0.42) PTGS2
SCHEMBL14232241 0.82 TRPV1 (0.52) PPARGPPARAPTGS2TRPV1
SCHEMBL15779727 0.82 PPARA (0.51) PPARGPPARAPTGS2S1PR1S1PR3
SCHEMBL5015897 0.81 TRPV1 (0.47) PPARGPPARAPTGS2TRPV1S1PR1
SCHEMBL5016692 0.81 TRPV1 (0.47) PPARGPPARAPTGS2TRPV1S1PR1
SCHEMBL5016274 0.81 TRPV1 (0.47) PPARGPPARAPTGS2TRPV1S1PR1
SCHEMBL28009344 0.81 S1PR1 (0.44) PPARGPPARAS1PR1S1PR3LPL
SCHEMBL249138 0.80 MTNR1A (0.50) PPARGPPARAPTGS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9796727-B2 Field effect transistor NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2017-10-24 US disclosed
EP-2402348-B1 FIELD EFFECT TRANSISTOR NIPPON KAYAKU KK (JP) 2017-04-12 EP disclosed
EP-2402348-A1 FIELD EFFECT TRANSISTOR Hiroshima University (JP) 2012-01-04 EP disclosed