Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 4/20 | 0.53 |
| ▸ | PPARA | Q07869 | 4/20 | 0.53 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.49 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.48 |
| ▸ | LPL | P06858 | 1/20 | 0.45 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.45 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27524531 | 0.95 | PPARG (0.46) | PPARGPPARAPTGS2TRPV1PDE10A | |
| SCHEMBL181330 | 0.90 | PPARG (0.53) | PPARGPPARAPTGS2TRPV1LPL | |
| SCHEMBL8399146 | 0.84 | AKT1 (0.47) | PTGS2PDE10A | |
| SCHEMBL27527363 | 0.81 | MTNR1A (0.60) | PTGS2 | |
| SCHEMBL22471924 | 0.81 | PPARG (0.41) | PPARGPPARALPLLIPG | |
| SCHEMBL27375571 | 0.80 | MTNR1A (0.58) | — | |
| SCHEMBL27343133 | 0.79 | MTNR1A (0.55) | — | |
| SCHEMBL10715691 | 0.78 | ALPL (0.42) | — | |
| SCHEMBL14232241 | 0.78 | TRPV1 (0.52) | PPARGPPARAPTGS2TRPV1 | |
| SCHEMBL25223402 | 0.77 | PPARA (0.59) | PPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1060761-C | New aryl (alkyl) propylamides process for preparing them and pharmaceutical compositions containing them | ADIR ET COMPAGUIE (FR) | 2001-01-17 | — | — | CN | disclosed |
| CN-1145897-A | New aryl (alkyl) propylamides process for preparing them and pharmaceutical compositions containing them | ADIR (FR) | 1997-03-26 | — | — | CN | disclosed |