Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 7/20 | 0.39 |
| ▸ | HSD17B1 | P14061 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | NQO2 | P16083 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 2/20 | 0.32 |
| ▸ | TOP1 | P11387 | 1/20 | 0.31 |
| ▸ | MPL | P40238 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13056079 | 0.85 | LMNA (0.42) | ADORA3HSD17B1LMNANPC1NQO2 | |
| SCHEMBL13075281 | 0.78 | GRM5 (0.39) | HSD17B1NPC1MAPTSMN1; SMN2 | |
| SCHEMBL13056071 | 0.69 | KCNMA1 (0.54) | — | |
| SCHEMBL13055747 | 0.62 | NPC1 (0.45) | HSD17B1LMNANPC1MAPTSMN1; SMN2 | |
| SCHEMBL13056184 | 0.61 | MEN1 (0.35) | HSD17B1LMNANPC1NQO2RXFP1 | |
| SCHEMBL1427131 | 0.61 | GCK (0.63) | MAPTSMN1; SMN2TP53 | |
| SCHEMBL2661529 | 0.61 | GCK (0.63) | MAPTSMN1; SMN2TP53 | |
| SCHEMBL13055688 | 0.60 | CCNE1 (0.45) | HSD17B1LMNANPC1MAPTSMN1; SMN2 | |
| SCHEMBL13056131 | 0.60 | NQO2 (0.33) | HSD17B1LMNANQO2MAPTSMN1; SMN2 | |
| SCHEMBL28224396 | 0.59 | CA12 (0.68) | LMNAMAPTSMN1; SMN2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3078377-A2 | NITAZOXANIDE AND TIZOXANIDE AS ANTI-VIRAL AGENTS | Romark Laboratories, L.C. (US) | 2016-10-12 | — | — | EP | disclosed |