Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 2/20 | 0.39 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | TYR | P14679 | 3/20 | 0.39 |
| ▸ | RRM1 | P23921 | 2/20 | 0.38 |
| ▸ | RRM2B | Q7LG56 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | PDE5A | O76074 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | GCK | P35557 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13055747 | 0.85 | NPC1 (0.45) | GRM5HSD17B1MAPTTYRRRM1 | |
| SCHEMBL18133035 | 0.78 | ADORA3 (0.39) | HSD17B1MAPTSMN1; SMN2NPC1 | |
| SCHEMBL22532026 | 0.70 | L3MBTL1 (0.56) | MAPTTYRSMN1; SMN2KMT2AL3MBTL1 | |
| SCHEMBL13055739 | 0.69 | KCNMA1 (0.60) | SMN1; SMN2MEN1KMT2ANPC1RAB9A | |
| SCHEMBL6918356 | 0.69 | GRM5 (0.74) | GRM5 | |
| SCHEMBL6918824 | 0.68 | GRM5 (0.73) | GRM5 | |
| SCHEMBL1797179 | 0.67 | GRM5 (0.56) | GRM5SMN1; SMN2NPC1RAB9AHTT | |
| SCHEMBL4757029 | 0.66 | RAB9A (0.50) | GRM5HSD17B1MAPTTYRSMN1; SMN2 | |
| SCHEMBL10114414 | 0.65 | GRM5 (0.68) | GRM5MAPTSMN1; SMN2MEN1HPGD | |
| SCHEMBL1794106 | 0.64 | GRM5 (0.54) | GRM5NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010132404-A1 | HALOALKYL HETEROARYL BENZAMIDE COMPOUNDS | ROMARK LABORATORIES L.C. (US) | 2010-11-18 | — | — | WO | disclosed |