SCHEMBL181332

SCHEMBL181332

CC(C)CC(C)(N)C(=O)O

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GGT1 P19440 1/20 0.45
GRM2 Q14416 2/20 0.44
GRM3 Q14832 1/20 0.44
ARG1 P05089 2/20 0.41
ARG2 P78540 2/20 0.41
NOS2 P35228 4/20 0.41
NOS1 P29475 2/20 0.41
BLM P54132 2/20 0.39
ALDH1A1 P00352 2/20 0.36
KDM4E B2RXH2 1/20 0.36
MEN1 O00255 1/20 0.36
USP2 O75604 1/20 0.36
EGFR P00533 1/20 0.36
CYP1A2 P05177 1/20 0.36
FYN P06241 1/20 0.36
POLB P06746 1/20 0.36
CYP3A4 P08684 1/20 0.36
GAA P10253 1/20 0.36
MAPT P10636 1/20 0.36
HPGD P15428 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL160650 1.00 GGT1 (0.45) GGT1GRM2GRM3ARG1ARG2
SCHEMBL160649 1.00 GGT1 (0.45) GGT1GRM2GRM3ARG1ARG2
Hydrochloric Acid SCHEMBL8995745 0.98 GGT1 (0.43) GGT1GRM2GRM3ARG1ARG2
Hydrochloric Acid SCHEMBL8995749 0.98 GGT1 (0.43) GGT1GRM2GRM3ARG1ARG2
Hydrochloric Acid SCHEMBL1025465 0.98 GGT1 (0.43) GGT1GRM2GRM3ARG1ARG2
Hydrochloric Acid SCHEMBL5764217 0.98 GGT1 (0.43) GGT1GRM2GRM3ARG1ARG2
SCHEMBL2721337 0.83 ARG1 (0.50) GGT1GRM2GRM3ARG1ARG2
SCHEMBL497269 0.83 GGT1 (0.43) GGT1GRM2GRM3ARG1ARG2
SCHEMBL27601801 0.82 SLC7A5 (0.40) GGT1GRM2GRM3ARG1ARG2
SCHEMBL1300782 0.81 GABRR1 (0.43) GGT1GRM2GRM3ARG1ARG2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1305 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260001928-A1 CRF2 RECEPTOR AGONISTS AND THEIR USE IN THERAPY CORTERIA PHARMACEUTICALS (FR) 2026-01-01 US claimed
EP-4482578-B1 CRF2 RECEPTOR AGONISTS AND THEIR USE IN THERAPY CORTERIA PHARMACEUTICALS (FR) 2025-12-24 EP claimed
EP-4568707-A1 PEPTIDE-BASED DELIVERY AGENT AND METHOD OF MAKING AND USING THE SAME EndoRel Biosciences LLC (US) 2025-06-18 EP claimed
CN-120076830-A Peptide-based delivery agents and methods of making and using the same 恩多雷尔生物科学有限责任公司 2025-05-30 CN claimed
CN-119823223-A Apelin peptide energy macrocycle and application thereof SOCPRA健康与人文科学有限公司 2025-04-15 CN claimed
CN-119431514-A Polypeptide derivative with triple targeting agonism of GCGR, GIPR and GLP-1R 南京知和医药科技有限公司 2025-02-14 CN claimed
EP-4482578-A1 CRF2 RECEPTOR AGONISTS AND THEIR USE IN THERAPY Corteria Pharmaceuticals (FR) 2025-01-01 EP claimed
CN-118843638-A CRF2 receptor agonists and their use in therapy 科尔特瑞制药公司 2024-10-25 CN claimed
EP-4448547-A1 APELINERGIC MACROCYCLES AND USES THEREOF Socpra Sciences Santé Et Humaines S.E.C. (CA) 2024-10-23 EP claimed
CN-118829646-A Apelin peptide energy macrocycle and application thereof SOCPRA健康与人文科学有限公司 2024-10-22 CN claimed
WO-2007088099-A2 COMPOUNDS FOR THE TREATMENT OF ISCHEMIA AND NEURODEGENERATION ONCOREG AB (SE) 2007-08-09 WO claimed
WO-2007080194-A2 USE OF TPP II INHIBITORS IN COMBINATION WITH GAMMA-IRRADIATION FOR THE TREATMENT OF CANCER ONCOREG AB (SE) 2007-07-19 WO claimed
US-7132394-B2 PTH-like peptides ABIOGEN PHARMA S.P.A. (IT) 2006-11-07 US claimed
US-20060019902-A1 PTH-like peptides ABIOGEN PHARMA S.P.A. (IT) 2006-01-26 US claimed
EP-1619204-A1 PTH-like peptides Abiogen Pharma S.p.A. (IT) 2006-01-25 EP claimed
CN-1578786-A Linear basic compounds having NK-2 antagonistic activity and formulations thereof MENARINI RICERCHE SPA (IT) 2005-02-09 CN claimed
US-20040259930-A1 Linear basic compounds having nk-2 antagonist activity and formulations thereof MALESCI INSTITUTO FARMACOBIOLOGICO S.P.A. (IT) 2004-12-23 US claimed
EP-1442050-A2 LINEAR BASIC COMPOUNDS HAVING NK-2 ANTAGONIST ACTIVITY AND FORMULATIONS THEREOF MALESCI ISTITUTO FARMACOBIOLOGICO S.p.A. (IT) 2004-08-04 EP claimed
WO-2003037916-A2 LINEAR BASIC COMPOUNDS HAVING NK-2 ANTAGONIST ACTIVITY AND FORMULATIONS THEREOF MALESCI ISTITUTO FARMACOBIOLOGICO S.P.A. (IT) 2003-05-08 WO claimed
WO-1988002756-A2 PEPTIDE DERIVATIVES SANDOZ AG (CH) 1988-04-21 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040259930-A1 Linear basic compounds having nk-2 antagonist activity and formulations thereof BDKRB2, BDKRB1, TACR2 GGT1 4055/4885GRM2 907/4885GRM3 1374/4885
US-20260001928-A1 CRF2 RECEPTOR AGONISTS AND THEIR USE IN THERAPY GIPR, NPY2R, NPY1R GGT1 2692/4885GRM2 28/4885GRM3 41/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.