SCHEMBL181336

SCHEMBL181336

CCC(N(C)C)N1C(=O)C=CC1=O

nearest known ligand 0.39

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
MGLL Q99685 10/20 0.39
ALDH1A1 P00352 2/20 0.39
BLM P54132 2/20 0.39
GMNN O75496 1/20 0.39
LMNA P02545 1/20 0.39
MAPT P10636 1/20 0.39
THPO P40225 1/20 0.39
PMP22 Q01453 1/20 0.39
NPSR1 Q6W5P4 1/20 0.39
GSK3A P49840 1/20 0.33
GSK3B P49841 1/20 0.33
PTGS1 P23219 3/20 0.32
PTGS2 P35354 3/20 0.32
FAAH O00519 3/20 0.32
CYP1A2 P05177 1/20 0.31
HPGD P15428 1/20 0.31
CYP2C19 P33261 1/20 0.31
WRN Q14191 1/20 0.31
HIF1A Q16665 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL181715 0.81 MGLL (0.38) MGLLALDH1A1BLMGMNNLMNA
SCHEMBL11290725 0.74 CHRM2 (0.33) ALDH1A1LMNA
SCHEMBL9149761 0.74 TDP1 (0.47) ALDH1A1LMNAMAPTHPGD
SCHEMBL7882002 0.72 MGLL (0.46) MGLLALDH1A1BLMGMNNLMNA
SCHEMBL1535518 0.72 MGLL (0.46) MGLLALDH1A1BLMGMNNLMNA
SCHEMBL3863566 0.70 MGLL (0.44) MGLLALDH1A1BLMGMNNLMNA
SCHEMBL181550 0.70 MGLL (0.38) MGLLALDH1A1BLMGMNNLMNA
SCHEMBL209740 0.70 MGLL (0.44) MGLLALDH1A1BLMGMNNLMNA
SCHEMBL28890319 0.69 LMNA (0.35) LMNA
SCHEMBL1554094 0.68 MGLL (0.42) MGLLALDH1A1BLMGMNNLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2269695-B1 Cosmetic compositions comprising a combination of a copolymer and at least one amphoteric polymer. BEIERSDORF AG (DE) 2016-12-21 EP claimed
EP-1811013-B1 Foamable alcoholic composition GOJO IND INC (US) 2009-08-12 EP claimed
EP-2269695-B1 Cosmetic compositions comprising a combination of a copolymer and at least one amphoteric polymer. BEIERSDORF AG (DE) 2016-12-21 EP disclosed
EP-2402375-A1 POLYOLEFIN COPOLYMER, AQUEOUS DISPERSION USING SAID POLYOLEFIN COPOLYMER AND MANUFACTURING METHOD THEREFOR, AND LAMINATE USING SAID POLYOLEFIN COPOLYMER Unitika, Ltd. (JP) 2012-01-04 EP disclosed
WO-2011030096-A2 HAIR STYLING COMPOSITION PZ CUSSONS (INTERNATIONAL) LTD (GB) 2011-03-17 WO disclosed
EP-2269695-A1 Cosmetic compositions comprising a combination of a copolymer and at least one amphoteric polymer. Beiersdorf AG (DE) 2011-01-05 EP disclosed
EP-1539090-B1 NATURAL FEEL POLYMERS ISP INVESTMENTS INC (US) 2008-09-17 EP disclosed
EP-1712256-A1 Cosmetic compositions comprising a combination of a copolymer and at least one anionic and/or amphoteric polymer Beiersdorf Aktiengesellschaft (DE) 2006-10-18 EP disclosed
US-3962527-A Novel polymers and photographic elements containing same EASTMAN KODAK COMPANY (US) 1976-06-08 US disclosed