Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHUK | O15111 | 7/20 | 0.64 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.64 |
| ▸ | GABRG2 | P18507 | 3/20 | 0.64 |
| ▸ | GABRB3 | P28472 | 3/20 | 0.64 |
| ▸ | GABRA5 | P31644 | 3/20 | 0.64 |
| ▸ | GABRA3 | P34903 | 3/20 | 0.64 |
| ▸ | GABRA2 | P47869 | 3/20 | 0.64 |
| ▸ | GABRA6 | Q16445 | 3/20 | 0.64 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.64 |
| ▸ | GABRP | O00591 | 1/20 | 0.64 |
| ▸ | GABRD | O14764 | 1/20 | 0.64 |
| ▸ | IKBKB | O14920 | 1/20 | 0.64 |
| ▸ | AURKA | O14965 | 1/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.64 |
| ▸ | PIM1 | P11309 | 1/20 | 0.64 |
| ▸ | TOP1 | P11387 | 1/20 | 0.64 |
| ▸ | IDO1 | P14902 | 1/20 | 0.64 |
| ▸ | HPGD | P15428 | 1/20 | 0.64 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29386403 | 0.82 | CDK4 (0.57) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL149685 | 0.82 | CDK4 (0.57) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL12001022 | 0.82 | CDK4 (0.57) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL17154708 | 0.82 | CDK4 (0.57) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL19041639 | 0.82 | CDK4 (0.57) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL30300831 | 0.82 | CDK4 (0.57) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL3365890 | 0.82 | CDK4 (0.57) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL28009141 | 0.82 | CHUK (0.57) | CHUKGABRA1GABRG2GABRB3GABRA5 | |
| SCHEMBL31174326 | 0.81 | MKNK1 (0.57) | CHUKGABRA1GABRG2GABRB3GABRA5 | |
| SCHEMBL7647500 | 0.81 | AHR (0.61) | GABRA1GABRG2GABRB3GABRA5GABRA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115304597-A | Beta-carboline compounds and application thereof in preparing medicines for treating or preventing tumor diseases | 中国科学院深圳先进技术研究院 | 2022-11-08 | — | — | CN | disclosed |
| EP-3069392-B1 | COMPOUND WITH NOVEL SIX-MEMBERED RING STRUCTURE FOR USE IN ORGANIC ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2019-08-07 | — | — | EP | disclosed |
| US-10374167-B2 | Compound with novel six-membered ring structure for use in organic electronic devices | MERCK PATENT GMBH (DE) | 2019-08-06 | — | — | US | disclosed |
| US-20160301016-A1 | COMPOUND WITH NOVEL SIX-MEMBERED RING STRUCTURE FOR USE IN ORGANIC ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2016-10-13 | — | — | US | disclosed |
| US-20160301016-A1 | COMPOUND WITH NOVEL SIX-MEMBERED RING STRUCTURE FOR USE IN ORGANIC ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2016-10-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10374167-B2 | Compound with novel six-membered ring structure for use in organic electronic devices | OCIAD2, OCIAD1, NR1D2 | CHUK 3533/4885GABRA1 3476/4885GABRG2 4126/4885 |
| US-20160301016-A1 | COMPOUND WITH NOVEL SIX-MEMBERED RING STRUCTURE FOR USE IN ORGANIC ELECTRONIC DEVICES | OCIAD2, OCIAD1, NR1D2 | CHUK 3533/4885GABRA1 3476/4885GABRG2 4126/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.