Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRK1 | P41145 | 4/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | PYCR1 | P32322 | 1/20 | 0.37 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.36 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 1/20 | 0.34 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.34 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.34 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.34 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.34 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.34 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.32 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15307297 | 0.84 | SLC6A4 (0.40) | OPRK1OPRM1PYCR1SLC6A2SLC6A4 | |
| SCHEMBL18135500 | 0.84 | TAAR1 (0.39) | IDO1CYP1A2CYP2A6TAAR1CNR2 | |
| SCHEMBL15307316 | 0.84 | RIPK1 (0.41) | OPRK1PYCR1SLC6A2SLC6A4IDO1 | |
| SCHEMBL15307291 | 0.83 | ALDH1A1 (0.43) | OPRK1OPRM1SLC6A2CYP2C19NPSR1 | |
| SCHEMBL15307308 | 0.81 | PYCR1 (0.44) | PYCR1SLC6A2SLC6A4IDO1TAAR1 | |
| SCHEMBL18135516 | 0.81 | TAAR1 (0.50) | PYCR1SLC6A2TAAR1 | |
| SCHEMBL15307276 | 0.80 | CYP1A2 (0.37) | CYP2C19NPSR1CYP1A2ALDH1A1 | |
| SCHEMBL15307307 | 0.80 | CYP2A6 (0.43) | SLC6A2SLC6A4CYP2A6ALDH1A1TSHR | |
| SCHEMBL8040655 | 0.79 | PYCR1 (0.40) | OPRK1OPRM1PYCR1ADRB2ADRB1 | |
| SCHEMBL18135502 | 0.77 | S1PR1 (0.35) | PYCR1SLC6A2SLC6A4CYP2C19PSEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160297823-A1 | SUBSTITUTED AMINO TRIAZOLES, AND METHODS USING SAME | INSTITUTE FOR DRUG DISCOVERY, LLC | 2016-10-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160297823-A1 | SUBSTITUTED AMINO TRIAZOLES, AND METHODS USING SAME | CMA1, CHIA, AADAC | OPRK1 3252/4885OPRM1 3971/4885PYCR1 4057/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.