Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHIT1 | Q13231 | 1/20 | 0.52 |
| ▸ | MAPK14 | Q16539 | 11/20 | 0.47 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.42 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.42 |
| ▸ | KIT | P10721 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | HSPB1 | P04792 | 1/20 | 0.41 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.41 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.41 |
| ▸ | F10 | P00742 | 2/20 | 0.41 |
| ▸ | PARP1 | P09874 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16825819 | 0.86 | CHIT1 (0.52) | CHIT1MAPK14F10 | |
| SCHEMBL16825996 | 0.85 | HTR4 (0.52) | CHIT1ROCK2ROCK1HTR4F10 | |
| SCHEMBL16825729 | 0.85 | CHIT1 (0.71) | CHIT1MAPK14F10 | |
| SCHEMBL16826087 | 0.83 | CHIT1 (0.48) | CHIT1OPRM1CYP2C9PARP1 | |
| SCHEMBL16825811 | 0.83 | MEN1 (0.56) | CHIT1PARP1 | |
| SCHEMBL16825728 | 0.83 | HTR7 (0.48) | CHIT1 | |
| SCHEMBL16826396 | 0.82 | CHIT1 (0.57) | CHIT1HTR4F10 | |
| SCHEMBL16825835 | 0.82 | CACNA1I (0.54) | CHIT1 | |
| SCHEMBL16825950 | 0.81 | CHIT1 (0.44) | CHIT1HTR4 | |
| SCHEMBL16825763 | 0.77 | RPS6KB1 (0.50) | CHIT1HTR4F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160297823-A1 | SUBSTITUTED AMINO TRIAZOLES, AND METHODS USING SAME | INSTITUTE FOR DRUG DISCOVERY, LLC | 2016-10-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160297823-A1 | SUBSTITUTED AMINO TRIAZOLES, AND METHODS USING SAME | CMA1, CHIA, AADAC | CHIT1 11/4885MAPK14 1983/4885ROCK2 4646/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.