Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 2/20 | 0.54 |
| ▸ | CA3 | P07451 | 2/20 | 0.54 |
| ▸ | CA6 | P23280 | 2/20 | 0.54 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.54 |
| ▸ | CASP1 | P29466 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.52 |
| ▸ | SRC | P12931 | 1/20 | 0.46 |
| ▸ | APP | P05067 | 3/20 | 0.43 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.41 |
| ▸ | MME | P08473 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9701361 | 0.89 | CYP2D6 (0.64) | CA3CA6CA14ALDH1A1HIF1A | |
| 4-Aminophenol SCHEMBL27835004 | 0.79 | ALDH1A1 (0.77) | THRBCA3CA6CA14ALDH1A1 | |
| SCHEMBL11255697 | 0.79 | AKR1C3 (0.50) | ALDH1A1HIF1ACYP2D6TDP1KDM4E | |
| SCHEMBL7258413 | 0.79 | CYP2D6 (0.46) | CA3CA6CA14CYP2D6SRC | |
| SCHEMBL68895 | 0.77 | AKR1C3 (0.51) | CA3CA6CA14CYP3A4ALOX15 | |
| 4-Aminophenol SCHEMBL6661712 | 0.77 | THRB (0.56) | THRBCA3CA6CA14ALDH1A1 | |
| SCHEMBL8727577 | 0.77 | CYP2D6 (0.48) | CA3CA6CA14ALDH1A1CYP3A4 | |
| SCHEMBL5517061 | 0.77 | AKR1C3 (0.51) | CA3CA6CA14CYP3A4ALOX15 | |
| SCHEMBL10785204 | 0.77 | AKR1C3 (0.51) | CA3CA6CA14CYP3A4ALOX15 | |
| 4-Aminophenol SCHEMBL28102190 | 0.76 | ALDH1A1 (0.93) | THRBCA3CA6CA14ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110124890-A1 | BATCH, SEMI-CONTINUOUS OR CONTINUOUS HYDROCHLORINATIONOF GLYCERIN WITH REDUCED VOLATILE CHLORINATED HYDROCARBON BY-PRODUCTS AND CHLOROACETONE LEVELS | BLUE CUBE IP LLC | 2011-05-26 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110124890-A1 | BATCH, SEMI-CONTINUOUS OR CONTINUOUS HYDROCHLORINATIONOF GLYCERIN WITH REDUCED VOLATILE CHLORINATED HYDROCARBON BY-PRODUCTS AND CHLOROACETONE LEVELS | GK, CHLSN, GLI2 | THRB 1534/4885CA3 924/4885CA6 323/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.