4-Aminophenol

4-Aminophenol

SCHEMBL6661712

C[C@H](N)C(=O)O.Nc1ccc(O)cc1

nearest known ligand 0.56

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
THRB P10828 2/20 0.56
CA14 Q9ULX7 2/20 0.56
ALDH1A1 P00352 1/20 0.56
CA3 P07451 1/20 0.56
CYP3A4 P08684 1/20 0.56
ALOX15 P16050 1/20 0.56
CA6 P23280 1/20 0.56
CASP1 P29466 1/20 0.56
HIF1A Q16665 1/20 0.56
HSD17B10 Q99714 1/20 0.56
SLC7A5 Q01650 1/20 0.47
APP P05067 3/20 0.45
ESR1 P03372 3/20 0.44
ESR2 Q92731 3/20 0.44
CYP19A1 P11511 2/20 0.44
TAAR1 Q96RJ0 3/20 0.42
SLC6A2 P23975 1/20 0.42
MME P08473 1/20 0.42
BLM P54132 2/20 0.41
KDM4E B2RXH2 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydroquinone SCHEMBL15655103 0.91 SLC7A5 (0.54) CA14ALDH1A1CA3CYP3A4ALOX15
Valine SCHEMBL5324319 0.86 SLC7A5 (0.58) THRBCA14ALDH1A1CA3CYP3A4
Benzidine SCHEMBL15658492 0.84 MMP1 (0.51) CA14ALDH1A1CYP3A4HSD17B10TAAR1
Phenol SCHEMBL2786796 0.82 CA12 (0.52) CA14CA3HIF1ASLC7A5TAAR1
Phenol SCHEMBL2786799 0.82 CA12 (0.52) CA14CA3HIF1ASLC7A5TAAR1
Aniline SCHEMBL27389527 0.82 TSHR (0.52) HIF1ASLC7A5TAAR1KDM4E
4-Aminophenol SCHEMBL3358484 0.81 CA3 (0.68) THRBCA14ALDH1A1CA3CYP3A4
4-Aminophenol SCHEMBL27835004 0.81 ALDH1A1 (0.77) THRBCA14ALDH1A1CA3CYP3A4
4-Aminophenol SCHEMBL27782121 0.79 ALDH1A1 (0.72) THRBCA14ALDH1A1CA3CYP3A4
4-Aminophenol SCHEMBL28102190 0.78 ALDH1A1 (0.93) THRBCA14ALDH1A1CA3CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1448991-A2 ACTIVATED ENZYME-LINKED DETECTION SYSTEMS FOR DETECTING AND QUANTIFYING NUCLEID ACIDS, ANTIGENS, ANTIBODIES AND OTHER ANALYTES FRAUNHOFER-GESELLSCHAFT ZUR FÖRDERUNG DER ANGEWANDTEN FORSCHUNG E.V. (DE) 2004-08-25 EP disclosed
WO-2002082078-A2 ACTIVATED ENZYME-LINKED DETECTION SYSTEMS FOR DETECTING AND QUANTIFYING NUCLEID ACIDS, ANTIGENS ANTIBODIES AND OTHER ANALYTES FRAUNHOFER-GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V. (DE) 2002-10-17 WO disclosed