Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BBOX1 | O75936 | 7/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.34 |
| ▸ | BCHE | P06276 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.33 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.33 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.33 |
| ▸ | PHF8 | Q9UPP1 | 2/20 | 0.32 |
| ▸ | KDM2A | Q9Y2K7 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | KDM6B | O15054 | 1/20 | 0.31 |
| ▸ | KDM5C | P41229 | 1/20 | 0.31 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.31 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.30 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Betaine SCHEMBL5167095 | 0.92 | TSHR (0.41) | BBOX1LMNAADRA1ABCHEACHE | |
| SCHEMBL9065100 | 0.90 | BBOX1 (0.42) | BBOX1ADRA1APLA2G2APLA2G4AEPHX2 | |
| SCHEMBL535704 | 0.85 | BBOX1 (0.39) | BBOX1BCHEACHE | |
| SCHEMBL11949115 | 0.84 | TSHR (0.35) | LMNABCHEACHETGFBR1KDM4E | |
| Betaine SCHEMBL5167081 | 0.84 | BBOX1 (0.44) | BBOX1LMNAADRA1AACHEPLA2G2A | |
| Betaine SCHEMBL5166537 | 0.84 | TSHR (0.39) | BBOX1LMNAADRA1APLA2G2APLA2G4A | |
| SCHEMBL6944920 | 0.83 | BBOX1 (0.50) | BBOX1ADRA1APLA2G2APLA2G4AEPHX2 | |
| SCHEMBL11949114 | 0.82 | ADRA1A (0.46) | BBOX1LMNAADRA1APLA2G2APLA2G4A | |
| Water SCHEMBL7088795 | 0.82 | BBOX1 (0.49) | BBOX1ADRA1APLA2G2APLA2G4AEPHX2 | |
| SCHEMBL16271548 | 0.81 | TGFBR1 (0.33) | BBOX1ADRA1APLA2G2ATGFBR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160296322-A1 | SYNTHETIC HEART VALVES COMPOSED OF ZWITTERIONIC POLYMERS | BOSTON SCIENTIFIC SCIMED, INC. | 2016-10-13 | — | — | US | disclosed |