Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | CHRM5 | P08912 | 3/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | BBOX1 | O75936 | 6/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | APEX1 | P27695 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.36 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | PGR | P06401 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16706627 | 0.90 | THRB (0.46) | TSHRACHETHRBCHRM5CHRM1 | |
| SCHEMBL10041769 | 0.89 | BBOX1 (0.53) | TSHRTHRBCHRM5CHRM1CHRM3 | |
| SCHEMBL23375334 | 0.88 | TSHR (0.55) | TSHRACHETHRBCHRM5CHRM1 | |
| SCHEMBL10300016 | 0.88 | THRB (0.53) | TSHRTHRBCHRM5CHRM1CHRM3 | |
| SCHEMBL21924148 | 0.87 | BBOX1 (0.50) | TSHRTHRBCHRM5CHRM1CHRM3 | |
| Water SCHEMBL7094496 | 0.87 | BBOX1 (0.51) | TSHRTHRBCHRM5CHRM1CHRM3 | |
| Bromide SCHEMBL725843 | 0.86 | THRB (0.52) | TSHRTHRBCHRM5CHRM1CHRM3 | |
| Hydrochloric Acid SCHEMBL1080732 | 0.85 | TSHR (0.47) | TSHRTHRBCHRM5CHRM1CHRM3 | |
| SCHEMBL4435789 | 0.85 | TSHR (0.47) | TSHRTHRBCHRM5CHRM1CHRM3 | |
| Hydrochloric Acid SCHEMBL5394034 | 0.85 | TSHR (0.61) | TSHRACHETHRBCHRM5CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170096637-A1 | Zwitterionic-Bias Material for Blood Cell Selection and Application Thereof | CHUNG YUAN CHRISTIAN UNIVERSITY (TW) | 2017-04-06 | — | — | US | disclosed |
| US-20160296322-A1 | SYNTHETIC HEART VALVES COMPOSED OF ZWITTERIONIC POLYMERS | BOSTON SCIENTIFIC SCIMED, INC. | 2016-10-13 | — | — | US | disclosed |