Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.49 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.49 |
| ▸ | HTR2A | P28223 | 2/20 | 0.49 |
| ▸ | HTR2B | P41595 | 2/20 | 0.49 |
| ▸ | HTR2C | P28335 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.47 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.47 |
| ▸ | DRD3 | P35462 | 1/20 | 0.47 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12124996 | 0.87 | HTR2A (0.51) | MEN1KMT2AKDM4EALDH1A1OPRM1 | |
| SCHEMBL16559754 | 0.85 | SIGMAR1 (0.40) | MEN1KMT2AKDM4EALDH1A1HTR2A | |
| SCHEMBL4238520 | 0.83 | MEN1 (0.63) | MEN1KMT2AKDM4EALDH1A1OPRM1 | |
| SCHEMBL18714753 | 0.83 | PRMT1 (0.60) | MEN1KMT2AKDM4EALDH1A1OPRM1 | |
| SCHEMBL4243270 | 0.81 | HTR2A (0.56) | MEN1KMT2AKDM4EALDH1A1OPRM1 | |
| SCHEMBL15308483 | 0.80 | PYCR1 (0.60) | KDM4EALDH1A1LMNASMN1; SMN2TAAR1 | |
| Hydrochloric Acid SCHEMBL8390076 | 0.80 | IDO1 (0.54) | MEN1KMT2AKDM4EALDH1A1OPRM1 | |
| SCHEMBL23374664 | 0.79 | SLC6A4 (0.59) | MEN1KMT2AKDM4EALDH1A1OPRM1 | |
| SCHEMBL2422764 | 0.79 | OPRM1 (0.48) | MEN1KMT2AKDM4EALDH1A1OPRM1 | |
| SCHEMBL11231510 | 0.79 | MEN1 (0.58) | MEN1KMT2AOPRM1OPRL1HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160297823-A1 | SUBSTITUTED AMINO TRIAZOLES, AND METHODS USING SAME | INSTITUTE FOR DRUG DISCOVERY, LLC | 2016-10-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160297823-A1 | SUBSTITUTED AMINO TRIAZOLES, AND METHODS USING SAME | CMA1, CHIA, AADAC | MEN1 2231/4885KMT2A 1919/4885KDM4E 2405/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.