Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 known ✓ | P08172 | 2/20 | 0.35 |
| ▸ | CHRM1 known ✓ | P11229 | 2/20 | 0.35 |
| ▸ | CHRM3 known ✓ | P20309 | 2/20 | 0.35 |
| ▸ | KDM4A | O75164 | 6/20 | 0.49 |
| ▸ | KDM2A | Q9Y2K7 | 6/20 | 0.49 |
| ▸ | MEN1 | O00255 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | THRB | P10828 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | CASP1 | P29466 | 2/20 | 0.39 |
| ▸ | HBB | P68871 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.39 |
| ▸ | CASP7 | P55210 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | ALPG | P10696 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18138134 | 0.80 | KMT2A (0.36) | KDM4AKDM2AMEN1MAPTKMT2A | |
| SCHEMBL18455466 | 0.78 | INSR (0.61) | APP | |
| SCHEMBL25018193 | 0.78 | HTT (0.40) | MEN1KMT2ASMN1; SMN2ALDH1A1HTT | |
| SCHEMBL12892564 | 0.77 | MMP14 (0.36) | MAPTKMT2ASMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL9882784 | 0.76 | KDM4A (0.63) | KDM4AKDM2AMEN1MAPTKMT2A | |
| SCHEMBL18135633 | 0.74 | KMT2A (0.33) | KDM4AKDM2AMEN1MAPTKMT2A | |
| SCHEMBL14984138 | 0.73 | KDM4A (0.79) | KDM4AKDM2AMEN1MAPTKMT2A | |
| SCHEMBL13645407 | 0.73 | KDM4A (0.84) | KDM4AKDM2AMEN1MAPTKMT2A | |
| SCHEMBL9551405 | 0.73 | HSD17B3 (0.54) | MEN1MAPTKMT2ASMN1; SMN2PTGS1 | |
| SCHEMBL12533259 | 0.72 | KDM4A (0.88) | KDM4AKDM2AMEN1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-120414597-A | Hydropower system capable of restraining ultralow frequency oscillation and oscillation restraining method | 铜陵学院 | 2025-08-01 | — | — | CN | disclosed |
| CN-117296173-A | membrane for proton conduction | 托马斯·翰翎 | 2023-12-26 | — | — | CN | disclosed |
| CN-108026278-B | Toughened poly (aryl ether sulfone)/poly (aryl ether ketone) blends | 索尔维特殊聚合物美国有限责任公司 | 2023-12-05 | — | — | CN | disclosed |
| CN-111601839-B | Process for preparing functionalized poly (aryl ether sulfone) polymers and block copolymers produced thereby | 索尔维特殊聚合物美国有限责任公司 | 2023-04-11 | — | — | CN | disclosed |
| CN-112543699-B | Method for manufacturing composite article | 罗地亚经营管理公司 | 2023-03-07 | — | — | CN | disclosed |
| CN-110799594-B | Layered structure | 索尔维特殊聚合物美国有限责任公司 | 2022-10-14 | — | — | CN | disclosed |
| CN-110621743-B | Polymer alloy comprising a sulfur-containing aromatic polymer and a VDF-based polymer | 索尔维特殊聚合物意大利有限公司 | 2022-09-30 | — | — | CN | disclosed |
| CN-109071937-B | Compatibilized polymer composition | 索尔维特殊聚合物美国有限责任公司 | 2022-09-06 | — | — | CN | disclosed |
| CN-110612330-B | Polymer alloy comprising sulfur-containing aromatic polymer and thermoplastic vulcanizate | 索尔维特殊聚合物意大利有限公司 | 2022-08-12 | — | — | CN | disclosed |
| CN-109843997-B | Porous article comprising a polymer and an additive, method for the production thereof and use thereof | 索尔维特殊聚合物美国有限责任公司 | 2022-06-03 | — | — | CN | disclosed |
| CN-110730709-B | Aromatic polymer particles, method for producing same and use thereof | 索尔维特殊聚合物美国有限责任公司 | 2022-03-22 | — | — | CN | disclosed |