Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR4 | P22455 | 8/20 | 0.50 |
| ▸ | FGFR1 | P11362 | 13/20 | 0.46 |
| ▸ | FGFR2 | P21802 | 2/20 | 0.41 |
| ▸ | FGFR3 | P22607 | 2/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18138303 | 0.87 | FGFR4 (0.37) | FGFR4FGFR1FGFR2FGFR3EGFR | |
| SCHEMBL18138305 | 0.86 | FGFR4 (0.36) | FGFR4FGFR1FGFR2FGFR3EGFR | |
| SCHEMBL18138307 | 0.79 | FGFR4 (0.43) | FGFR4FGFR1FGFR2FGFR3EGFR | |
| SCHEMBL18131245 | 0.79 | FGFR1 (0.39) | FGFR4FGFR1FGFR2FGFR3 | |
| SCHEMBL18138286 | 0.78 | FGFR3 (0.34) | FGFR4FGFR1FGFR2FGFR3 | |
| SCHEMBL18138306 | 0.77 | FGFR4 (0.44) | FGFR4FGFR1FGFR2FGFR3EGFR | |
| SCHEMBL18138366 | 0.73 | FGFR3 (0.32) | FGFR4FGFR1FGFR2FGFR3 | |
| SCHEMBL16665233 | 0.73 | FGFR1 (0.48) | FGFR4FGFR1FGFR2FGFR3 | |
| SCHEMBL18131198 | 0.73 | FGFR4 (0.79) | FGFR4FGFR1FGFR2FGFR3EGFR | |
| SCHEMBL17736227 | 0.72 | FGFR1 (0.49) | FGFR4FGFR1FGFR2FGFR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016164754-A1 | FGFR4 INHIBITORS | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2016-10-13 | — | — | WO | disclosed |