SCHEMBL18138397

SCHEMBL18138397

CCCCCCN(CCCCCC)C1CCCCN2CCCN=C12

nearest known ligand 0.33

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
CHRNB2 P17787 1/20 0.33
CHRNA7 P36544 1/20 0.33
CHRNA4 P43681 1/20 0.33
ALDH1A1 P00352 1/20 0.32
GBA1 P04062 1/20 0.31
NOS3 P29474 1/20 0.30
NOS1 P29475 1/20 0.30
NOS2 P35228 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL580781 0.94 NOS3 (0.32) NOS3NOS1NOS2
SCHEMBL809739 0.88 CHRNB2 (0.32) CHRNB2CHRNA7CHRNA4ALDH1A1
SCHEMBL10717970 0.82 NOS3 (0.31) NOS3NOS1NOS2
SCHEMBL809736 0.80 SLC29A1 (0.36) ALDH1A1
SCHEMBL17215357 0.77 CHRNB2 (0.40) CHRNB2CHRNA7CHRNA4ALDH1A1NOS3
SCHEMBL809756 0.77 CHRNB2 (0.40) CHRNB2CHRNA7CHRNA4ALDH1A1NOS3
SCHEMBL8147596 0.77 CHRNB2 (0.40) CHRNB2CHRNA7CHRNA4ALDH1A1NOS3
SCHEMBL809794 0.77 CHRNB2 (0.40) CHRNB2CHRNA7CHRNA4ALDH1A1NOS3
SCHEMBL809360 0.74 INMT (0.37) NOS3NOS1NOS2
SCHEMBL17328037 0.72 NOS3 (0.36) CHRNB2CHRNA7CHRNA4ALDH1A1NOS3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3081612-A1 PHOTOCURABLE COMPOSITION HAVING ADHESIVE PROPERTIES Cemedine Co., Ltd. (JP) 2016-10-19 EP disclosed