Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHBP | P24387 | 1/20 | 0.46 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.45 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.45 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.38 |
| ▸ | CSF3R | Q99062 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 3/20 | 0.36 |
| ▸ | MAOA | P21397 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HTR7 | P34969 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20578335 | 0.87 | MTNR1A (0.46) | MTNR1AMTNR1BLMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL20578400 | 0.82 | ALDH1A1 (0.51) | CRHBPCRHR2PTPN1LMNASMN1; SMN2 | |
| SCHEMBL18300919 | 0.80 | CRHBP (0.52) | CRHBPCRHR2PTPN1MTNR1AMTNR1B | |
| SCHEMBL18030723 | 0.79 | CARM1 (0.47) | CRHBPCRHR2PTPN1MTNR1AMTNR1B | |
| SCHEMBL7207372 | 0.79 | CRHBP (0.54) | CRHBPCRHR2PTPN1LMNASMN1; SMN2 | |
| SCHEMBL29892730 | 0.79 | CRHBP (0.54) | CRHBPCRHR2PTPN1LMNASMN1; SMN2 | |
| SCHEMBL18138726 | 0.78 | MTNR1A (0.57) | CRHBPCRHR2PTPN1MTNR1AMTNR1B | |
| SCHEMBL11813069 | 0.75 | RAD52 (0.40) | CRHBPCRHR2MTNR1AMTNR1BLMNA | |
| SCHEMBL9652432 | 0.74 | TSHR (0.51) | CRHBPCRHR2MTNR1AMTNR1BSMN1; SMN2 | |
| SCHEMBL18030730 | 0.73 | MTNR1A (0.54) | CRHBPCRHR2PTPN1MTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3081553-B1 | SULFONAMIDE DERIVATIVE OR PHARMACEUTICALLY ACCEPTABLE ACID ADDITION SALT THEREOF | UNIV TSUKUBA (JP) | 2018-12-12 | — | — | EP | disclosed |
| EP-3081553-A1 | SULFONAMIDE DERIVATIVE OR PHARMACEUTICALLY ACCEPTABLE ACID ADDITION SALT THEREOF | University of Tsukuba (JP) | 2016-10-19 | — | — | EP | disclosed |
| CN-106029633-A | Sulfonamide derivative or pharmaceutically acceptable acid addition salt thereof | 国立大学法人筑波大学 | 2016-10-12 | — | — | CN | disclosed |