SCHEMBL18142154

SCHEMBL18142154

O=C(CCc1ccccc1)[C@@H]1CCCN1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CTSC P53634 1/20 0.49
HTR2C P28335 1/20 0.47
HTR2B P41595 1/20 0.47
KEAP1 Q14145 1/20 0.46
NPC1 O15118 2/20 0.44
TDP1 Q9NUW8 1/20 0.44
ALDH1A1 P00352 2/20 0.43
L3MBTL1 Q9Y468 1/20 0.43
CYP2C19 P33261 1/20 0.43
TAAR1 Q96RJ0 3/20 0.43
FFAR1 O14842 1/20 0.43
POLB P06746 2/20 0.42
ELANE P08246 1/20 0.42
SMN1; SMN2 Q16637 2/20 0.42
HPGD P15428 1/20 0.42
EPHX2 P34913 3/20 0.41
TP53 P04637 1/20 0.41
EPHX1 P07099 1/20 0.41
TSHR P16473 1/20 0.41
RAB9A P51151 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4677228 0.91 EPHX2 (0.49) CTSCHTR2CHTR2BNPC1TDP1
SCHEMBL6099087 0.90 EPHX1 (0.50) CTSCHTR2CHTR2BSMN1; SMN2EPHX2
SCHEMBL27763495 0.85 HTR2C (0.41) CTSCHTR2CHTR2BFFAR1
SCHEMBL13769699 0.85 HTR2C (0.47) HTR2CHTR2BALDH1A1POLBEPHX1
Proline SCHEMBL9015317 0.84 CTSC (0.51) CTSCHTR2CHTR2BNPC1TAAR1
SCHEMBL7582887 0.81 TDP1 (0.46) CTSCHTR2CHTR2BKEAP1NPC1
SCHEMBL11549712 0.79 HTR2C (0.44) CTSCHTR2CHTR2BKEAP1NPC1
SCHEMBL2089398 0.79 HTR2C (0.60) CTSCHTR2CHTR2BNPC1ALDH1A1
SCHEMBL2089397 0.79 HTR2C (0.60) CTSCHTR2CHTR2BNPC1ALDH1A1
SCHEMBL27330173 0.79 KEAP1 (0.43) KEAP1NPC1TDP1ALDH1A1FFAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2790805-B1 SEPARATION OF HYDROCARBON FAMILIES OR OF INDIVIDUAL COMPONENTS BY CONSECUTIVE EXTRACTIVE DISTILLATIONS PERFORMED IN A SINGLE COLUMN SIME S R L (IT) 2016-10-19 EP claimed