Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.62 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.62 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.62 |
| ▸ | MAPT | P10636 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.60 |
| ▸ | MEN1 | O00255 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.60 |
| ▸ | NAMPT | P43490 | 2/20 | 0.60 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.60 |
| ▸ | PKM | P14618 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.59 |
| ▸ | GAA | P10253 | 1/20 | 0.59 |
| ▸ | CA1 | P00915 | 2/20 | 0.59 |
| ▸ | CA2 | P00918 | 2/20 | 0.59 |
| ▸ | CA9 | Q16790 | 2/20 | 0.59 |
| ▸ | CA12 | O43570 | 1/20 | 0.59 |
| ▸ | NPC1 | O15118 | 1/20 | 0.58 |
| ▸ | RAB9A | P51151 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6267575 | 0.88 | CYP1A2 (0.65) | CYP1A2CYP3A4CYP2C9CYP2C19MAPT | |
| SCHEMBL10107716 | 0.87 | APEX1 (0.66) | LMNAL3MBTL1MEN1KMT2AALDH1A1 | |
| SCHEMBL1812144 | 0.86 | MEN1 (0.65) | CYP1A2CYP3A4CYP2C9CYP2C19LMNA | |
| SCHEMBL1813399 | 0.85 | GAA (0.66) | CYP1A2CYP3A4CYP2C9CYP2C19MAPT | |
| SCHEMBL28475160 | 0.85 | NAMPT (0.63) | CYP1A2CYP3A4CYP2C9CYP2C19MAPT | |
| SCHEMBL10333227 | 0.83 | KMT2A (0.72) | CYP1A2CYP3A4CYP2C9CYP2C19MAPT | |
| SCHEMBL27380778 | 0.82 | RAB9A (0.60) | ALDH1A1CA1CA2CA9NPC1 | |
| SCHEMBL29356619 | 0.82 | ALDH1A1 (0.77) | MAPTMEN1KMT2ANAMPTPKM | |
| SCHEMBL6270935 | 0.82 | ALDH1A1 (0.77) | MAPTMEN1KMT2ANAMPTPKM | |
| SCHEMBL26368509 | 0.81 | KMT2A (0.65) | CYP1A2CYP3A4CYP2C19MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8314269-B2 | N-(1-methyl-2phenylethyl)benzamide derivatives | BAYER CROPSCIENCE AG (DE) | 2012-11-20 | — | — | US | claimed |
| US-20110237678-A1 | N-(1-METHYL-2PHENYLETHYL)BENZAMIDE DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2011-09-29 | — | — | US | claimed |
| US-20090156682-A1 | N-(1-Methyl-2Phenylethyl)Benzamide Derivatives | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2009-06-18 | — | — | US | claimed |
| EP-1960350-A1 | NEW N-(1-METHYL-2PHENYLETHYL)BENZAMIDE DERIVATIVES | BAYER CROPSCIENCE SA (FR) | 2008-08-27 | — | — | EP | claimed |
| WO-2007060162-A1 | NEW N-(1-METHYL-2PHENYLETHYL)BENZAMIDE DERIVATIVES | BAYER CROPSCIENCE SA (FR) | 2007-05-31 | — | — | WO | claimed |
| US-8314269-B2 | N-(1-methyl-2phenylethyl)benzamide derivatives | BAYER CROPSCIENCE AG (DE) | 2012-11-20 | — | — | US | disclosed |
| US-20110237678-A1 | N-(1-METHYL-2PHENYLETHYL)BENZAMIDE DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2011-09-29 | — | — | US | disclosed |
| US-7951973-B2 | N-(1-methyl-2Phenylethyl)benzamide derivatives | BAYER CROPSCIENCE AG (DE) | 2011-05-31 | — | — | US | disclosed |
| US-20090156682-A1 | N-(1-Methyl-2Phenylethyl)Benzamide Derivatives | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2009-06-18 | — | — | US | disclosed |
| EP-1960350-A1 | NEW N-(1-METHYL-2PHENYLETHYL)BENZAMIDE DERIVATIVES | BAYER CROPSCIENCE SA (FR) | 2008-08-27 | — | — | EP | disclosed |
| WO-2007060162-A1 | NEW N-(1-METHYL-2PHENYLETHYL)BENZAMIDE DERIVATIVES | BAYER CROPSCIENCE SA (FR) | 2007-05-31 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090156682-A1 | N-(1-Methyl-2Phenylethyl)Benzamide Derivatives | CYP51A1, CYP1A2, CYP1A1 | CYP1A2 2/4885CYP3A4 20/4885CYP2C9 36/4885 |
| US-20110237678-A1 | N-(1-METHYL-2PHENYLETHYL)BENZAMIDE DERIVATIVES | CYP51A1, CYP1A2, CYP1A1 | CYP1A2 2/4885CYP3A4 16/4885CYP2C9 35/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.