SCHEMBL18145367

SCHEMBL18145367

O=C(OCCOC(=O)Oc1cccc2[nH]nnc12)Oc1cccc2[nH]nnc12

nearest known ligand 0.37

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
ELANE P08246 3/20 0.37
MAPT P10636 3/20 0.32
SMN1; SMN2 Q16637 2/20 0.32
NPC1 O15118 1/20 0.32
RAB9A P51151 1/20 0.32
MTNR1A P48039 2/20 0.30
MTNR1B P49286 2/20 0.30
TYMS P04818 1/20 0.30
MEN1 O00255 1/20 0.30
ALDH1A1 P00352 1/20 0.30
LMNA P02545 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5526503 0.90 ELANE (0.32) ELANE
SCHEMBL7565875 0.90 ELANE (0.36) ELANEMTNR1AMTNR1B
SCHEMBL44289 0.89 MAPT (0.33) MAPTLMNA
Ethylene Glycol SCHEMBL4451270 0.87 MAPT (0.31) MAPTLMNA
SCHEMBL14690221 0.86 MAPT (0.32) MAPTLMNA
SCHEMBL6943583 0.85 KMT2A (0.44) MAPTSMN1; SMN2MEN1ALDH1A1LMNA
SCHEMBL3410233 0.85 CYP3A4 (0.37) MAPTSMN1; SMN2MEN1ALDH1A1LMNA
SCHEMBL8844752 0.83 MAPT (0.33) MAPTLMNA
SCHEMBL44290 0.81 LMNA (0.35) MAPTMEN1ALDH1A1LMNAKMT2A
SCHEMBL17783612 0.80 FABP5 (0.39) KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210308323-A1 COMPOSITION AND KITS FOR PSEUDOPLASTIC MICROGEL MATRICES ROCHAL INDUSTRIES, LLC (US) 2021-10-07 US claimed
EP-3283057-B1 COMPOSITION AND KITS FOR PSEUDOPLASTIC MICROGEL MATRICES ROCHAL IND LLC (US) 2021-07-28 EP claimed
EP-3283057-A1 COMPOSITION AND KITS FOR PSEUDOPLASTIC MICROGEL MATRICES Rochal Industries, LLC (US) 2018-02-21 EP claimed
WO-2016168196-A1 COMPOSITION AND KITS FOR PSEUDOPLASTIC MICROGEL MATRICES ROCHAL INDUSTRIES, LLC (US) 2016-10-20 WO claimed
US-20160303281-A1 COMPOSITION AND KITS FOR PSEUDOPLASTIC MICROGEL MATRICES ROCHAL INDUSTRIES, LLC (US) 2016-10-20 US claimed
US-11590259-B2 Composition and kits for pseudoplastic microgel matrices ROCHAL TECHNOLOGIES LLC (US) 2023-02-28 US disclosed
US-20210308323-A1 COMPOSITION AND KITS FOR PSEUDOPLASTIC MICROGEL MATRICES ROCHAL INDUSTRIES, LLC (US) 2021-10-07 US disclosed
EP-3283057-B1 COMPOSITION AND KITS FOR PSEUDOPLASTIC MICROGEL MATRICES ROCHAL IND LLC (US) 2021-07-28 EP disclosed
EP-3283057-A1 COMPOSITION AND KITS FOR PSEUDOPLASTIC MICROGEL MATRICES Rochal Industries, LLC (US) 2018-02-21 EP disclosed
WO-2016168196-A1 COMPOSITION AND KITS FOR PSEUDOPLASTIC MICROGEL MATRICES ROCHAL INDUSTRIES, LLC (US) 2016-10-20 WO disclosed
US-20160303281-A1 COMPOSITION AND KITS FOR PSEUDOPLASTIC MICROGEL MATRICES ROCHAL INDUSTRIES, LLC (US) 2016-10-20 US disclosed