Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | METAP2 | P50579 | 1/20 | 0.35 |
| ▸ | METAP1 | P53582 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA7 | P43166 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL44289 | 0.88 | MAPT (0.33) | LMNAMETAP2METAP1HDAC6MAPT | |
| SCHEMBL8844752 | 0.88 | MAPT (0.33) | LMNAMETAP2METAP1HDAC6MAPT | |
| SCHEMBL27464332 | 0.87 | ATM (0.34) | LMNAMETAP2METAP1HDAC6MAPT | |
| Fluorene SCHEMBL23748025 | 0.87 | MAPK8 (0.38) | LMNAMETAP2METAP1HDAC6MAPT | |
| SCHEMBL2534586 | 0.85 | MEN1 (0.38) | LMNAMETAP2METAP1HDAC6MAPT | |
| SCHEMBL14690221 | 0.85 | MAPT (0.32) | LMNAMETAP2METAP1HDAC6MAPT | |
| SCHEMBL7707716 | 0.85 | SLC22A6 (0.44) | LMNAMAPTADORA2AHSP90AA1L3MBTL1 | |
| SCHEMBL6155017 | 0.84 | LMNA (0.54) | LMNAMETAP2METAP1HDAC6MAPT | |
| Ethylene Glycol SCHEMBL4451270 | 0.83 | MAPT (0.31) | LMNAMETAP2METAP1HDAC6MAPT | |
| SCHEMBL818765 | 0.81 | ELANE (0.37) | MAPTMAOBADORA2AKMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 302 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11952461-B2 | Siloxy polyethylene glycol and derivatives thereof | SUNBIO, INC. (KR) | 2024-04-09 | — | — | US | claimed |
| US-20220298302-A1 | SILOXY POLYETHYLENE GLYCOL AND DERIVATIVES THEREOF | SUNBIO, INC. (KR) | 2022-09-22 | — | — | US | claimed |
| CN-107708675-B | Compositions and kits for pseudoplastic microgel matrices | 罗查尔科技有限责任公司 | 2022-07-22 | — | — | CN | claimed |
| US-20110238000-A1 | POLYMER-CONJUGATED ALBUMIN HYDROGELS FOR CONTROLLED RELEASE OF THERAPEUTIC AGENTS | TECHNION RESEARCH AND DEVELOPMENT FOUNDATION LTD. (IL) | 2011-09-29 | — | — | US | claimed |
| JP-4764630-B2 | — | — | 2011-09-07 | — | — | JP | claimed |
| WO-2010064252-A2 | POLYMER-CONJUGATED ALBUMIN HYDROGELS FOR CONTROLLED RELEASE OF THERAPEUTIC AGENTS | TECHNION RESEARCH & DEVELOPMENT FOUNDATION LTD. (IL) | 2010-06-10 | — | — | WO | claimed |
| US-20100112660-A1 | Method for Derivatization of Proteins Using Hydrostatic Pressure | BAROFOLD, INC. (US) | 2010-05-06 | — | — | US | claimed |
| WO-2009155102-A2 | METHOD FOR DERIVATIZATION OF PROTEINS USING HYDROSTATIC PRESSURE | BAROFOLD, INC. (US) | 2009-12-23 | — | — | WO | claimed |
| EP-1259563-B1 | METHOD FOR THE PREPARATION OF 1-BENZOTRIAZOLYL CARBONATE ESTERS OF WATER SOLUBLE POLYMERS. | NEKTAR THERAPEUTICS AL CORP (US) | 2009-03-04 | — | — | EP | claimed |
| US-20060233854-A1 | Matrix composed of a naturally-occurring protein backbone cross linked by a synthetic polymer and methods of generating and using same | REGENTIS BIOMATERIALS LTD. | 2006-10-19 | — | — | US | claimed |
| US-20060194940-A1 | 2-methylbutyraldehyde diethyl acetal end capped polyoxyethylene glycol; polyalkylene oxide, polyivnylpyrrolidone, polyvinyl alcohol, polyoxazoline etc. endcapped with polyetherpolyamine copolymers or oligomers covalently attached to diacetal tetramethylene group | NEKTAR THERAPEUTICS AL, CORPORATION (US) | 2006-08-31 | — | — | US | claimed |
| JP-2005538224-A | — | — | 2005-12-15 | — | — | JP | claimed |
| CN-1688631-A | Water soluble polymer alkanals | NEKTAR THERAPEUTICS AL CORP (US) | 2005-10-26 | — | — | CN | claimed |
| EP-1546235-A2 | WATER-SOLUBLE POLYMER ALKANALS | Nektar Therapeutics Al, Corporation (US) | 2005-06-29 | — | — | EP | claimed |
| US-20040116649-A1 | Polyoxyethylene glycol; purity, storage stability | NEKTAR THERAPEUTICS | 2004-06-17 | — | — | US | claimed |
| WO-2004022630-A2 | WATER-SOLUBLE POLYMER ALKANALS | NEKTAR THERAPEUTICS AL, CORPORATION (US) | 2004-03-18 | — | — | WO | claimed |
| CN-118772395-A | Method for preparing releasable polymeric reagents | 尼克塔治疗公司 | 2024-10-15 | — | — | CN | disclosed |
| US-20240299561-A1 | HISTIDINE-SELECTIVE POLYMER REAGENTS | NEKTAR THERAPEUTICS | 2024-09-12 | — | — | US | disclosed |
| WO-2004022630-A2 | WATER-SOLUBLE POLYMER ALKANALS | NEKTAR THERAPEUTICS AL, CORPORATION (US) | 2004-03-18 | — | — | WO | disclosed |
| US-20040024151-A1 | Functionalized perylene tetracarboxylic acid diimides | MAX-PLANCK-GESELLSCHAFT DER WISSENSCHAFTENE. V. (DE) | 2004-02-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240299561-A1 | HISTIDINE-SELECTIVE POLYMER REAGENTS | HNMT, PHYKPL, PHPT1 | LMNA 4185/4885METAP2 1192/4885METAP1 877/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.