SCHEMBL8844752

SCHEMBL8844752

O=C(Oc1cccc2[nH]nnc12)C(=O)Oc1cccc2[nH]nnc12

nearest known ligand 0.33

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.33
PARP1 P09874 1/20 0.33
HPSE Q9Y251 1/20 0.33
LMNA P02545 1/20 0.33
METAP2 P50579 1/20 0.33
METAP1 P53582 1/20 0.33
HDAC6 Q9UBN7 1/20 0.33
KDM4E B2RXH2 1/20 0.31
POLB P06746 1/20 0.31
MAOB P27338 1/20 0.31
ADORA2A P29274 1/20 0.31
PDE5A O76074 1/20 0.31
HSP90AA1 P07900 1/20 0.31
ATM Q13315 1/20 0.30
TDP1 Q9NUW8 1/20 0.30
FLT3 P36888 1/20 0.30
USP2 O75604 1/20 0.30
SRD5A2 P31213 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27464332 0.92 ATM (0.34) MAPTPARP1HPSELMNAMETAP2
SCHEMBL44289 0.90 MAPT (0.33) MAPTPARP1HPSELMNAMETAP2
SCHEMBL818765 0.89 ELANE (0.37) MAPTPARP1HPSEMAOBADORA2A
SCHEMBL44290 0.88 LMNA (0.35) MAPTLMNAMETAP2METAP1HDAC6
SCHEMBL14690221 0.87 MAPT (0.32) MAPTPARP1LMNAMETAP2METAP1
SCHEMBL2534586 0.87 MEN1 (0.38) MAPTPARP1LMNAMETAP2METAP1
SCHEMBL7707716 0.87 SLC22A6 (0.44) MAPTLMNAKDM4EPOLBADORA2A
Ethylene Glycol SCHEMBL4451270 0.84 MAPT (0.31) MAPTLMNAMETAP2METAP1HDAC6
SCHEMBL30442196 0.83 ACHE (0.39) MAPTLMNAKDM4ETDP1
SCHEMBL8590357 0.83 THRB (0.38) MAPTLMNAKDM4EPOLBTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4347544-A1 PROCESSES FOR THE VAPOR PHASE HYDROGENATION OF ALDEHYDES Dow Technology Investments LLC (US) 2024-04-10 EP disclosed
WO-2022250790-A1 PROCESSES FOR THE VAPOR PHASE HYDROGENATION OF ALDEHYDES DOW TECHNOLOGY INVESTMENTS LLC (US) 2022-12-01 WO disclosed
EP-2970074-A1 HETEREOCYCLIC AGENT AS CATALYTIC STABILIZING AGENT IN A HYDROFORMYLATION PROCESS Dow Technology Investments LLC (US) 2016-01-20 EP disclosed
WO-2014149915-A1 HETEREOCYCLIC AGENT AS CATALYTIC STABILIZING AGENT IN A HYDROFORMYLATION PROCESS DOW TECHNOLOGY INVESTMENTS LLC (US) 2014-09-25 WO disclosed
WO-2013025197-A1 OXALATE SORBENTS FOR MERCURY REMOVAL EMPIRE TECHNOLOGY DEVELOPMENT LLC (US) 2013-02-21 WO disclosed
WO-1997020798-A1 IMPROVED METAL-LIGAND COMPLEX CATALYZED PROCESSES UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) 1997-06-12 WO disclosed