Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | ERN1 | O75460 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1424023 | 0.87 | PTGS1 (0.46) | ALDH1A1SMN1; SMN2MAPTPOLBKDM4E | |
| SCHEMBL24841250 | 0.87 | CYP3A4 (0.46) | ALDH1A1SMN1; SMN2ACHEMAPTHPGD | |
| SCHEMBL1814206 | 0.85 | LMNA (0.45) | ALDH1A1SMN1; SMN2MAPTHPGDMAPK1 | |
| SCHEMBL3001741 | 0.82 | ALDH1A1 (0.38) | ALDH1A1SMN1; SMN2ACHEHPGDL3MBTL1 | |
| SCHEMBL6841350 | 0.79 | TSHR (0.45) | ALDH1A1MAPTHPGDL3MBTL1MEN1 | |
| SCHEMBL6475041 | 0.75 | AKR1B1 (0.47) | ALDH1A1SMN1; SMN2MAPTMAPK1MEN1 | |
| SCHEMBL1813981 | 0.74 | CNR2 (0.43) | ALDH1A1SMN1; SMN2MAPTL3MBTL1MEN1 | |
| SCHEMBL12553293 | 0.73 | ALDH1A1 (0.49) | ALDH1A1SMN1; SMN2ACHEMAPTNPSR1 | |
| SCHEMBL12653057 | 0.72 | TAAR1 (0.54) | ALDH1A1ACHEMAPTHPGDMAPK1 | |
| SCHEMBL12269963 | 0.72 | CNR2 (0.41) | ALDH1A1SMN1; SMN2MAPTHPGDNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110213160-A1 | 2,4,6-Phenyl-Substituted Derivatives | BAYER CROPSCIENCE AG (DE) | 2011-09-01 | — | — | US | disclosed |
| US-20110195842-A1 | 2,4,6-Phenyl-Substituted Cyclic Ketoenols | BAYER CROPSCIENCE AG (DE) | 2011-08-11 | — | — | US | disclosed |
| US-7947704-B2 | 2,4,6-phenyl-substituted cyclic ketoenols | BAYER CROPSCIENCE AG (DE) | 2011-05-24 | — | — | US | disclosed |
| US-20070298968-A1 | 2,4,6-Phenyl-Substituted Cyclic Ketoenols | BAYER CROPSCIENCE AG (DE) | 2007-12-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070298968-A1 | 2,4,6-Phenyl-Substituted Cyclic Ketoenols | CYP4X1, KCNE1, KDM4E | ALDH1A1 2441/4885SMN1; SMN2 4169/4885ACHE 288/4885 |
| US-20110195842-A1 | 2,4,6-Phenyl-Substituted Cyclic Ketoenols | CYP4X1, KCNE1, KDM4E | ALDH1A1 2441/4885SMN1; SMN2 4169/4885ACHE 288/4885 |
| US-20110213160-A1 | 2,4,6-Phenyl-Substituted Derivatives | CYP4X1, KDM4E, KCNE1 | ALDH1A1 2129/4885SMN1; SMN2 4082/4885ACHE 278/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.