SCHEMBL1814738

SCHEMBL1814738

CC(C)CN1C(=O)c2c(Cl)c(Cl)c(Cl)c(Cl)c2C1=O

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA9 Q16790 3/20 0.40
CA1 P00915 2/20 0.40
CA2 P00918 2/20 0.40
CA7 P43166 2/20 0.40
CA12 O43570 1/20 0.40
CA4 P22748 1/20 0.37
CNR1 P21554 1/20 0.34
TRPA1 O75762 1/20 0.34
KMT2A Q03164 2/20 0.33
EP300 Q09472 2/20 0.33
DUSP3 P51452 1/20 0.33
MPO P05164 1/20 0.33
NR1H3 Q13133 1/20 0.33
NR1H2 P55055 1/20 0.32
PIK3CD O00329 1/20 0.31
KDM4E B2RXH2 1/20 0.31
MEN1 O00255 1/20 0.31
ALDH1A1 P00352 1/20 0.31
MAPT P10636 1/20 0.31
HPGD P15428 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1818098 0.82 KMT2A (0.37) CA9CA1CA2CA7CA12
SCHEMBL14341825 0.79 CA9 (0.38) CA9CA1CA2CA7CA12
SCHEMBL3678744 0.75 F2 (0.43) CA9CA1CA2CA7CA12
SCHEMBL23665440 0.74 EP300 (0.40) CNR1KMT2AEP300MPOMEN1
SCHEMBL10935097 0.74 CA9 (0.38) CA9CA1CA2CA7CA12
SCHEMBL12163243 0.74 CA1 (0.46) CA9CA1CA2CA7CA12
SCHEMBL1813132 0.74 CA1 (0.50) CA9CA1CA2CA7CA12
SCHEMBL28854193 0.74 CA1 (0.37) CA9CA1CA2CA7CA12
SCHEMBL23665372 0.72 GAA (0.33) KMT2AEP300MPOPIK3CDKDM4E
SCHEMBL15977327 0.72 ALDH1A1 (0.41) KMT2AEP300MPOPIK3CDKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2496636-B1 MORE FLAME-RETARDANT POLYCARBONATE COMPOSITION FOR USE IN EXTRUDED PRODUCTS COVESTRO DEUTSCHLAND AG (DE) 2019-05-15 EP disclosed
US-10272654-B2 Polycarbonate composition having improved flame resistance for extrusion applications COVESTRO DEUTSCHLAND AG (DE) 2019-04-30 US disclosed
CN-102725341-B Polycarbonate compositions with improved flame retardancy for extrusion applications BAYER MATERIALSCIENCE AG 2014-09-17 CN disclosed
EP-2496639-B1 POLYCARBONATE COMPOSITION HAVING IMPROVED FLAME RESISTANCE FOR EXTRUSION APPLICATIONS BAYER IP GMBH (DE) 2013-12-25 EP disclosed
EP-2207844-B1 FLAME-RETARDANT POLYCARBONATES COMPRISING POLYOLS BAYER IP GMBH (DE) 2013-07-03 EP disclosed
CN-101842429-B Flame retardant polycarbonate comprising a polyol BAYER MATERIALSCIENCE AG 2013-03-27 CN disclosed
CN-102725341-A Polycarbonate compositions with improved flame retardancy for extrusion applications BAYER MATERIALSCIENCE AG 2012-10-10 CN disclosed
US-20120244359-A1 POLYCARBONATE COMPOSITION HAVING IMPROVED FLAME RESISTANCE FOR EXTRUSION APPLICATIONS BAYER INTELLECTUAL PROPERTY GMBH (DE) 2012-09-27 US disclosed
US-20120231278-A1 POLYCARBONATE COMPOSITION HAVING IMPROVED FLAME RESISTANCE FOR EXTRUSION APPLICATIONS BAYER INTELLECTUAL PROPERTY GMBH (DE) 2012-09-13 US disclosed
CN-102666695-A Polycarbonate compositions with improved flame retardancy for extrusion applications BAYER MATERIALSCIENCE A G 2012-09-12 CN disclosed
US-5326800-A Use of salts in combination with halogenated phthalimides for flameproof finishing of glass fibre-containing polycarbonate moulded members BAYER AKTIENGESELLSCHAFT (DE) 1994-07-05 US disclosed
EP-0561238-A2 Use of salts in combination with halogenated phthalimides for flame protection of polycarbonates containing glass fibres BAYER AG (DE) 1993-09-22 EP disclosed
EP-0219014-A2 Flame retardant elastomeric compositions GENERAL ELECTRIC COMPANY (US) 1987-04-22 EP disclosed
US-4639486-A POLYETHERIMIDE ESTER AND HALOGENATED MATERIAL GENERAL ELECTRIC COMPANY (US) 1987-01-27 US disclosed
US-4552911-A TETRAHALOPHTHALIMIDE BAYER AKTIENGESELLSCHAFT (DE) 1985-11-12 US disclosed
EP-0042561-B1 FIRE-PROOFED MOULDING MASSES BASED ON AROMATIC THERMOPLASTIC POLYESTERS, PROCESS FOR ITS PREPARATION AND USE IN THE PRODUCTION OF SHAPED ARTICLES BAYER AG (DE) 1985-03-27 EP disclosed
EP-0086353-A1 Polycarbonate moulding compounds with flame resistance BAYER AG (DE) 1983-08-24 EP disclosed
US-4366276-A Flame-resistant moulding materials based on thermoplastic aromatic polyesters and polyesters carbonates, a process for their production and their use in the production of moulded bodies BAYER AKTIENGESELLSCHAFT (DE) 1982-12-28 US disclosed
EP-0042561-A1 Fire-proofed moulding masses based on aromatic thermoplastic polyesters, process for its preparation and use in the production of shaped articles BAYER AG (DE) 1981-12-30 EP disclosed
US-4208489-A AN ALKALI METAL SALT AND A TETRAHALOGENOPHTHALIMIDE BAYER AKTIENGESELLSCHAFT (DE) 1980-06-17 US disclosed