SCHEMBL18150175

SCHEMBL18150175

Nc1ccc(Cl)c(C(=O)NCc2ccccn2)c1

nearest known ligand 0.71

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
HPGD P15428 5/20 0.71
ALDH1A1 P00352 2/20 0.71
SMN1; SMN2 Q16637 2/20 0.66
RAB9A P51151 3/20 0.62
POLB P06746 1/20 0.60
KDM4E B2RXH2 1/20 0.56
LMNA P02545 2/20 0.56
USP2 O75604 1/20 0.56
ADORA2A P29274 1/20 0.56
ADORA1 P30542 1/20 0.56
L3MBTL1 Q9Y468 1/20 0.55
HTT P42858 2/20 0.54
GLA P06280 1/20 0.54
MAPT P10636 1/20 0.54
NPC1 O15118 2/20 0.53
KMT2A Q03164 2/20 0.53
CYP1A2 P05177 1/20 0.53
CYP3A4 P08684 1/20 0.53
CYP2C19 P33261 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30171601 0.90 HPGD (0.77) HPGDALDH1A1SMN1; SMN2RAB9APOLB
SCHEMBL29451525 0.85 NPC1 (0.60) HPGDALDH1A1SMN1; SMN2RAB9AKDM4E
SCHEMBL11627488 0.84 HPGD (1.00) HPGDALDH1A1SMN1; SMN2RAB9APOLB
SCHEMBL27737857 0.82 HPGD (0.62) HPGDALDH1A1SMN1; SMN2RAB9APOLB
SCHEMBL21019010 0.81 POLB (0.58) HPGDALDH1A1SMN1; SMN2RAB9APOLB
SCHEMBL10324599 0.80 KDM4E (0.67) HPGDALDH1A1SMN1; SMN2RAB9APOLB
SCHEMBL9158747 0.80 CA1 (0.60) HPGDLMNAL3MBTL1KMT2ACYP1A2
SCHEMBL10324601 0.80 KDM4E (0.70) HPGDALDH1A1RAB9APOLBKDM4E
SCHEMBL11887850 0.79 HPGD (1.00) HPGDALDH1A1SMN1; SMN2RAB9APOLB
SCHEMBL11625676 0.78 LMNA (0.74) HPGDALDH1A1SMN1; SMN2RAB9APOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3578542-B1 COMPOSITIONS HAVING PESTICIDAL UTILITY AND PROCESSES RELATED THERETO CORTEVA AGRISCIENCE LLC (US) 2025-11-12 EP disclosed
CN-107466291-B Molecules having pesticidal utility, and intermediates, compositions and methods related thereto 美国陶氏益农公司 2021-08-20 CN disclosed
EP-3578542-A1 MOLECULES HAVING PESTICIDAL UTILITY, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES, RELATED THERETO Dow AgroSciences LLC (US) 2019-12-11 EP disclosed
EP-3578542-A1 MOLECULES HAVING PESTICIDAL UTILITY, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES, RELATED THERETO Dow AgroSciences LLC (US) 2019-12-11 EP disclosed
EP-3283458-B1 MOLECULES HAVING PESTICIDAL UTILITY, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES, RELATED THERETO DOW AGROSCIENCES LLC (US) 2019-05-22 EP disclosed
EP-3283458-B1 MOLECULES HAVING PESTICIDAL UTILITY, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES, RELATED THERETO DOW AGROSCIENCES LLC (US) 2019-05-22 EP disclosed
US-20180007911-A1 Molecules having pesticidal utility, and intermediates, compositions, and processes, related thereto DOW AGROSCIENCES LLC (US) 2018-01-11 US disclosed
US-9795140-B2 Molecules having pesticidal utility, and intermediates, compositions, and processes, related thereto DOW AGROSCIENCES LLC (US) 2017-10-24 US disclosed
US-9795140-B2 Molecules having pesticidal utility, and intermediates, compositions, and processes, related thereto DOW AGROSCIENCES LLC (US) 2017-10-24 US disclosed
US-20160302418-A1 Molecules having pesticidal utility, and intermediates, compositions, and processes, related thereto DOW AGROSCIENCES LLC (US) 2016-10-20 US disclosed
WO-2016168058-A1 MOLECULES HAVING PESTICIDAL UTILITY, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES, RELATED THERETO DOW AGROSCIENCES LLC (US) 2016-10-20 WO disclosed
US-20160302418-A1 Molecules having pesticidal utility, and intermediates, compositions, and processes, related thereto DOW AGROSCIENCES LLC (US) 2016-10-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160302418-A1 Molecules having pesticidal utility, and intermediates, compositions, and processes, related thereto ACHE, DDT, MLYCD HPGD 997/4885ALDH1A1 443/4885SMN1; SMN2 3645/4885
US-20180007911-A1 Molecules having pesticidal utility, and intermediates, compositions, and processes, related thereto ACHE, DDT, MLYCD HPGD 997/4885ALDH1A1 443/4885SMN1; SMN2 3645/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.