SCHEMBL1815124

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL13733119	0.89	HTT (0.47)	HTTCYP1A2SLC26A6ALDH1A1THRB
	SCHEMBL23791456	0.81	NPSR1 (0.39)	HTTALDH1A1KDM4EMAPTKMT2A
	SCHEMBL7400591	0.79	HTT (0.52)	HTTCYP1A2SLC26A6ALDH1A1MAPT
	SCHEMBL14941595	0.78	HTT (0.47)	HTTCYP1A2ALDH1A1HPGDKDM4E
	SCHEMBL9461101	0.76	HTT (0.50)	HTTCYP1A2ALDH1A1HPGDKDM4E
	SCHEMBL15284739	0.76	HTT (0.50)	HTTCYP1A2ALDH1A1HPGDKDM4E
	SCHEMBL13733197	0.75	HTT (0.49)	HTTCYP1A2SLC26A6ALDH1A1HPGD
	SCHEMBL3559987	0.75	HTT (0.49)	HTTCYP1A2ALDH1A1HPGDKDM4E
	SCHEMBL15932046	0.74	GPR119 (0.38)	ALDH1A1GAAMAPTNPC1RAB9A
	SCHEMBL17653859	0.74	SMN1; SMN2 (0.40)	HTTGAAMAPTMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.