Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL9 | O00512 | 5/20 | 0.45 |
| ▸ | CTNNB1 | P35222 | 5/20 | 0.45 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.40 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 2/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.38 |
| ▸ | FEN1 | P39748 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | SUV39H2 | Q9H5I1 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.36 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18152574 | 0.91 | BCL9 (0.46) | BCL9CTNNB1SCN9APDK2IDO1 | |
| SCHEMBL18152455 | 0.91 | BCL9 (0.48) | BCL9CTNNB1SCN9APDK2CA12 | |
| SCHEMBL18152400 | 0.87 | BCL9 (0.46) | BCL9CTNNB1SCN9APDK2CA12 | |
| SCHEMBL16709793 | 0.83 | RAB9A (0.47) | SCN9APDK2IDO1CA12CA1 | |
| SCHEMBL18152551 | 0.82 | BCL9 (0.48) | BCL9CTNNB1SCN9APDK2CA12 | |
| SCHEMBL16593033 | 0.81 | SUV39H2 (0.44) | IDO1CA12CA1CA2CA9 | |
| SCHEMBL31500921 | 0.81 | TTR (0.50) | SCN9APDK2IDO1CA12CA1 | |
| SCHEMBL18152291 | 0.78 | BCL9 (0.47) | BCL9CTNNB1SCN9APDK2CA12 | |
| SCHEMBL18165177 | 0.77 | BCL9 (0.48) | BCL9CTNNB1SCN9APDK2CA12 | |
| SCHEMBL18165162 | 0.77 | MGLL (0.53) | SCN9APDK2IDO1CA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016168524-A1 | SUBSTITUTED N-([1,1'-BIPHENYL]-3-YL)-[1,1'-BIPHENYL]-3-CARBOXAMIDE ANALOGS AS INHIBITORS FOR BETA-CATENIN/B-CELL LYMPHOMA 9 INTERACTIONS | UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) | 2016-10-20 | — | — | WO | disclosed |