Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL9 | O00512 | 3/20 | 0.46 |
| ▸ | CTNNB1 | P35222 | 3/20 | 0.46 |
| ▸ | PPARD | Q03181 | 3/20 | 0.42 |
| ▸ | PPARA | Q07869 | 1/20 | 0.41 |
| ▸ | RARG | P13631 | 8/20 | 0.41 |
| ▸ | RARA | P10276 | 7/20 | 0.41 |
| ▸ | RARB | P10826 | 7/20 | 0.41 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.41 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18152328 | 0.91 | BCL9 (0.45) | BCL9CTNNB1SCN9APDK2IDO1 | |
| SCHEMBL18152551 | 0.91 | BCL9 (0.48) | BCL9CTNNB1PPARDPPARARARG | |
| SCHEMBL18152291 | 0.87 | BCL9 (0.47) | BCL9CTNNB1RARGRARARARB | |
| SCHEMBL18152455 | 0.82 | BCL9 (0.48) | BCL9CTNNB1SCN9APDK2 | |
| SCHEMBL28624037 | 0.82 | SMN1; SMN2 (0.47) | IDO1 | |
| SCHEMBL926919 | 0.82 | RAB9A (0.49) | SCN9APDK2IDO1 | |
| SCHEMBL18690622 | 0.81 | RXRA (0.46) | RARGRARARARBIDO1 | |
| SCHEMBL18152403 | 0.78 | PDK2 (0.42) | PPARDPPARASCN9APDK2 | |
| SCHEMBL18152400 | 0.78 | BCL9 (0.46) | BCL9CTNNB1SCN9APDK2 | |
| SCHEMBL18165177 | 0.78 | BCL9 (0.48) | BCL9CTNNB1SCN9APDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016168524-A1 | SUBSTITUTED N-([1,1'-BIPHENYL]-3-YL)-[1,1'-BIPHENYL]-3-CARBOXAMIDE ANALOGS AS INHIBITORS FOR BETA-CATENIN/B-CELL LYMPHOMA 9 INTERACTIONS | UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) | 2016-10-20 | — | — | WO | disclosed |