Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 1/20 | 0.49 |
| ▸ | BCL9 | O00512 | 7/20 | 0.48 |
| ▸ | CTNNB1 | P35222 | 7/20 | 0.48 |
| ▸ | PTGER1 | P34995 | 3/20 | 0.44 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.43 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18152331 | 0.91 | BCL9 (0.49) | SYKBCL9CTNNB1PTGER1LMNA | |
| SCHEMBL20025819 | 0.83 | SLC6A4 (0.45) | SYKPTPN7LMNAHPGDSLC6A4 | |
| SCHEMBL18165180 | 0.83 | RARB (0.53) | SYKBCL9CTNNB1PTPN7HPGD | |
| SCHEMBL20021919 | 0.82 | BCL9 (0.54) | SYKBCL9CTNNB1PTPN7SLC6A4 | |
| SCHEMBL3629085 | 0.81 | RAB9A (0.51) | SYKPTGER1LMNAHPGDTDP1 | |
| SCHEMBL16055873 | 0.81 | CYP11B1 (0.55) | PTGER1PTPN7LMNAHPGDSLC6A4 | |
| SCHEMBL3631211 | 0.81 | LMNA (0.56) | SYKPTGER1LMNAHPGDPTGS2 | |
| SCHEMBL18152413 | 0.81 | CTNNB1 (0.77) | BCL9CTNNB1 | |
| SCHEMBL18152277 | 0.80 | LMNA (0.51) | LMNAHPGDTDP1L3MBTL1MAPT | |
| SCHEMBL20025844 | 0.79 | CTNNB1 (0.81) | BCL9CTNNB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016168524-A1 | SUBSTITUTED N-([1,1'-BIPHENYL]-3-YL)-[1,1'-BIPHENYL]-3-CARBOXAMIDE ANALOGS AS INHIBITORS FOR BETA-CATENIN/B-CELL LYMPHOMA 9 INTERACTIONS | UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) | 2016-10-20 | — | — | WO | disclosed |