Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.48 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.40 |
| ▸ | BCL9 | O00512 | 6/20 | 0.39 |
| ▸ | CTNNB1 | P35222 | 6/20 | 0.39 |
| ▸ | SYK | P43405 | 1/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.39 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.39 |
| ▸ | FEN1 | P39748 | 2/20 | 0.39 |
| ▸ | RXRA | P19793 | 1/20 | 0.39 |
| ▸ | RXRB | P28702 | 1/20 | 0.39 |
| ▸ | RXRG | P48443 | 1/20 | 0.39 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.38 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.38 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20025817 | 0.91 | PTGDR2 (0.47) | PTGDR2PTGER1BCL9CTNNB1SYK | |
| SCHEMBL18152302 | 0.80 | FFAR4 (0.42) | PTGER1BCL9CTNNB1SYKFFAR1 | |
| SCHEMBL18152365 | 0.78 | SYK (0.49) | PTGER1BCL9CTNNB1SYK | |
| SCHEMBL18076083 | 0.76 | GRM2 (0.57) | — | |
| SCHEMBL20025818 | 0.75 | BCL9 (0.48) | BCL9CTNNB1SYKALDH1A1 | |
| SCHEMBL18152284 | 0.75 | PTGDR2 (0.49) | PTGDR2BCL9CTNNB1SYKFFAR4 | |
| SCHEMBL16046595 | 0.74 | S1PR1 (0.41) | RXRARXRBRXRG | |
| SCHEMBL3787470 | 0.73 | PTGDR2 (0.57) | PTGDR2PTGER1RXRARXRBRXRG | |
| SCHEMBL18152413 | 0.72 | CTNNB1 (0.77) | BCL9CTNNB1 | |
| SCHEMBL18152321 | 0.72 | PTGER1 (0.58) | PTGER1BCL9CTNNB1FEN1RXRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016168524-A1 | SUBSTITUTED N-([1,1'-BIPHENYL]-3-YL)-[1,1'-BIPHENYL]-3-CARBOXAMIDE ANALOGS AS INHIBITORS FOR BETA-CATENIN/B-CELL LYMPHOMA 9 INTERACTIONS | UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) | 2016-10-20 | — | — | WO | disclosed |