Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.42 |
| ▸ | C5AR1 | P21730 | 3/20 | 0.40 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.40 |
| ▸ | BCL9 | O00512 | 6/20 | 0.40 |
| ▸ | CTNNB1 | P35222 | 6/20 | 0.40 |
| ▸ | SYK | P43405 | 1/20 | 0.40 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.39 |
| ▸ | GPR34 | Q9UPC5 | 1/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.38 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20025817 | 0.81 | PTGDR2 (0.47) | C5AR1PTGER1BCL9CTNNB1SYK | |
| Trifluoroacetic Acid SCHEMBL18152377 | 0.80 | PTGDR2 (0.48) | FFAR4FFAR1PTGER1BCL9CTNNB1 | |
| SCHEMBL18152365 | 0.79 | SYK (0.49) | PTGER1BCL9CTNNB1SYK | |
| SCHEMBL18076083 | 0.79 | GRM2 (0.57) | CYP11B1CYP11B2 | |
| SCHEMBL20025818 | 0.74 | BCL9 (0.48) | C5AR1BCL9CTNNB1SYKCYP11B1 | |
| SCHEMBL18152391 | 0.73 | MGLL (0.58) | C5AR1BCL9CTNNB1ALDH1A1 | |
| SCHEMBL18152413 | 0.73 | CTNNB1 (0.77) | BCL9CTNNB1 | |
| SCHEMBL18152321 | 0.73 | PTGER1 (0.58) | PTGER1BCL9CTNNB1 | |
| SCHEMBL18076202 | 0.72 | SQOR (0.42) | CYP11B1CYP11B2 | |
| SCHEMBL20025844 | 0.71 | CTNNB1 (0.81) | BCL9CTNNB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016168524-A1 | SUBSTITUTED N-([1,1'-BIPHENYL]-3-YL)-[1,1'-BIPHENYL]-3-CARBOXAMIDE ANALOGS AS INHIBITORS FOR BETA-CATENIN/B-CELL LYMPHOMA 9 INTERACTIONS | UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) | 2016-10-20 | — | — | WO | disclosed |